Rosuva Tablet 10 Milligrams (Rosuvastatin Calcium)

Adult dose

For adult patients with primary hypercholesterolemia, this medication can be taken at any time of the day regardless of meals. The initial dose is 5 milligrams once daily, and if necessary, it can be adjusted to a maintenance dose of 10 milligrams once daily. The maintenance dose should be adjusted based on patient condition at intervals of at least 4 weeks, up to a maximum of 20 milligrams per day.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the dosage is administered once daily ranging from 5 milligrams to 20 milligrams. The dosage should be adjusted individually based on therapeutic goals at intervals of at least 4 weeks.

This medication should not be used in certain patients. For example, patients with an allergy to any components of this drug, unexplained elevation of liver enzymes, patients with muscle diseases, those with severe renal impairment, and women who are pregnant or breastfeeding should not take this medication. Additionally, high-dose use of this medication is prohibited in patients at high risk of muscle-related diseases. Such patients include those with moderate to severe renal impairment, hypothyroidism, a family history of muscle disease, and alcohol dependence. This medication contains lactose; therefore, it should not be administered to patients with lactose intolerance or related genetic disorders. When administering this drug, caution is necessary for those with excessive alcohol consumption or a history of liver disease, and repeated liver function tests are recommended before and during treatment. If symptoms of muscle pain or weakness occur, inform a physician immediately and check for muscle damage through blood tests. Particularly, if muscle enzyme levels rise significantly, the medication should be discontinued. It is safe to stop taking this medication during acute severe illness or post-surgical conditions. This medication may interact with other drugs; therefore, it is essential to inform about any other medications being taken, especially when combined with those that may increase the risk of muscle toxicity. Women who may become pregnant should use appropriate contraception and should not take this medication during pregnancy. There is no specific antidote for overdose, so treatment should be symptomatic, and liver function and muscle enzyme tests are needed. This medication does not significantly affect driving or operating machinery, but dizziness may occur; caution is advised. Finally, if symptoms such as skin rash, itching, severe muscle pain, or jaundice occur during treatment, consult medical personnel immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), liver abnormalities (jaundice), acute renal failure, oliguria, thrombocytopenia, increased serum creatinine, severe muscle weakness, ocular muscle weakness, rhabdomyolysis, severe skin reactions, severe allergic reactions, respiratory problems, severe neurological symptoms, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• hives
• muscle pain
• weakness

This medication is sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the drug's efficacy and safety over time.

Appearance

Pink round film-coated tablets

Package unit

For domestic use: 28 tablets (14 tablets/PTP X 2), for export: 56 tablets (14 tablets/PTP X 4)