Ezistar Tablets 10/20 Milligrams

Adult dose

This medication is taken once daily in the evening without regard to meals. For patients with primary hypercholesterolemia, the dosage range is 10/10 mg to 10/40 mg daily, with a commonly recommended starting dose of 10/20 mg per day. Patients with lower needs for reducing LDL cholesterol may start with 10/10 mg once daily. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg once daily in the evening.

This medication may cause serious side effects such as myopathy and rhabdomyolysis. These side effects can include muscle pain and weakness, accompanied by a significant increase in specific blood enzyme levels. The risk may be higher when taking high doses of this medication or when used in conjunction with certain other drugs. Thus, if you experience muscle pain or weakness, you should inform your doctor immediately, and discontinue the medication if necessary. This medication should not be administered to patients with allergies to its components, severely impaired liver function, or to women who are pregnant or breastfeeding. Additionally, caution is required when used in conjunction with certain antifungals, antibiotics, and immunosuppressants, as the risk of side effects may increase. It should be administered with caution to patients with severe muscle weakness or ocular myasthenia; if these symptoms worsen, medication use should be discontinued. This medication may cause liver function abnormalities, so regular liver function tests should be conducted, particularly for patients with a history of liver disease. If you experience unexplained muscle pain, tenderness, or weakness while taking this medication, inform healthcare personnel immediately; when receiving a prescription for new medications, be sure to inform them that you are taking this medication. Special care is required when using this medication in the elderly or children, especially as it is not recommended for children under 10 years of age. This medication may raise blood sugar levels, thus patients at risk for diabetes should monitor their blood glucose levels regularly. In case of overdose, as there is no specific antidote, general treatment according to symptoms will be administered. Finally, patients taking this medication should limit consumption of certain foods like grapefruit juice, and exercise caution to avoid drug interactions with other medications.

Serious side effects

• Myopathy/rhabdomyolysis
• angioedema
• rash
• urticaria
• pancreatitis
• hepatitis
• cholestatic jaundice
• severe fatigue
• severe muscle weakness
• ocular muscle weakness

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• nausea
• abdominal pain
• constipation

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is important to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. This helps to preserve the efficacy of the medication for an extended period.

Appearance

White to off-white, biconvex rectangular tablet

Package unit

30 tablets (10 tablets/PTPX3)