Coxvito Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day if needed. From the second day of administration, the recommended dose as needed is 200 mg per dose twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

People who regularly consume alcohol more than three times a day must consult with a doctor or pharmacist before taking this medication. There is a risk of gastrointestinal bleeding. This medication can increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke, so patients with a history of cardiovascular disease or risk factors should exercise particular caution. Use the lowest effective dose for the shortest duration, and consult healthcare personnel immediately if cardiovascular symptoms appear. This medication can cause serious gastrointestinal adverse reactions, such as gastrointestinal perforation, ulcers, and bleeding, therefore patients with a history of gastrointestinal diseases, elderly patients, or those taking it for a long time should be especially careful. If symptoms like epigastric pain, dyspepsia, black stools, or hematemesis occur, seek medical attention immediately. This medication is not to be administered to patients with specific allergies, severe liver or kidney disorders, active peptic ulcer disease, heart failure, pregnant women, or nursing mothers. Patients with impaired liver or kidney function, asthma, heart failure, hypertension, or diabetes should use this medication with caution, and regular monitoring may be necessary. Dizziness or drowsiness may occur while taking this medication; therefore, it is advisable to avoid driving or operating machinery. This medication may interact with other drugs, so if you are taking other medications, be sure to inform your healthcare provider. Women who are pregnant or planning a pregnancy should consult a doctor before using this medication, as it may affect reproductive capacity. If taken for a long time, this medication necessitates regular blood tests and liver and kidney function tests to monitor for any abnormalities. In case of overdose, symptoms such as nausea, vomiting, and lethargy may occur, and immediate medical attention should be sought. Keep out of reach of children and avoid transferring to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion state, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injuries, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, elevated CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various parts of the body, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, sensory decline, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergy exacerbation, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change glomerulonephritis, menstrual disorders, female infertility, chest pain, hallucinations, nosebleeds, speech disorders, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, anaphylactic reactions

This medication should be stored in a tightly sealed container to prevent air exposure and kept at room temperature, between 15 to 30 degrees Celsius. Proper storage helps maintain its efficacy and prevents degradation.

Appearance

White or light yellow powder in a white hard capsule with yellow stripes on the top and bottom

Package unit

30 capsules (10 capsules/PTP×3), 100 capsules/bottle