Dexinofen Syrup (Dexibuprofen)

Adult dose

Children aged 2 years and older and adults generally adjust the dose according to body weight. The single dose should be 5–7 mg/kg of dexibuprofen and taken as needed every 4–6 hours. The total daily dose should not exceed 4 times or 28 mg/kg.

Child dose

Children over 6 months of age should take a dose of 0.4–0.6 mL/kg (5–7 mg/kg of dexibuprofen) as needed every 4–6 hours, not exceeding a maximum of 4 times a day (28 mg/kg).

This medication should be consulted with a physician or pharmacist if taken by individuals who regularly consume more than 3 alcoholic beverages per day, as it may cause gastrointestinal bleeding. It contains non-steroidal anti-inflammatory drug (NSAID) components which may increase the risk of cardiovascular diseases, so individuals with heart conditions or risk factors should exercise caution. This medication can cause serious adverse reactions such as gastrointestinal bleeding, ulcers, and perforations, and special caution should be exercised in the elderly or those with a history of gastrointestinal diseases. Patients with a history of peptic ulcers, severe liver dysfunction, kidney dysfunction, severe hypertension, or severe heart failure should not take this medication. Those with a history of peptic ulcers, bleeding tendencies, liver disease, kidney disease, hypertension, or elderly patients should take this medication with caution, and when taken with aspirin, its effects may decrease or the risk of side effects may increase. This medication may rarely cause allergic reactions, blood disorders, gastrointestinal bleeding, skin rashes, liver dysfunction, or kidney dysfunction, so if any abnormal symptoms occur, discontinue use immediately and consult a physician. Regular blood tests and liver/kidney function tests are required for long-term use, and it is recommended to use the minimum effective dose for the shortest duration possible. This medication should be used in conjunction with antibiotics for the treatment of infectious inflammation, and alternative treatment methods should be considered for patients at high risk of gastrointestinal bleeding. Patients with hypertension should closely monitor blood pressure changes while taking this medication, and patients with heart failure or edema should use it cautiously due to the risk of fluid retention. Using this medication in conjunction with other NSAIDs, glucocorticoids, anticoagulants, etc., may increase the risk of side effects, so it should be taken only after consulting a specialist. During pregnancy, especially in the third trimester, this medication may be harmful to the fetus; thus, it is advisable for pregnant women or those who may become pregnant to avoid taking it. If nursing, this medication may pass into breast milk and cause adverse reactions in infants, so nursing should be stopped or medication should be discontinued. Extra caution is needed for children and the elderly when taking this medication, and in children, the dosage is strictly based on their weight. In case of overdose, emergency treatment such as gastric lavage or inducing vomiting should be performed immediately, and it should be stored in a safe place out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, shock symptoms, hypotension, hypertension, thrombocytopenia, impaired platelet function, aplastic anemia, hemolytic anemia, granulocytopenia, eosinophilia, peptic ulcers, gastrointestinal bleeding, perforation, ulcerative colitis, bloody stools, gastritis, pancreatitis, Stevens-Johnson syndrome, Lyell syndrome, drug rashes accompanied by systemic syndromes, jaundice, asthma attacks, aseptic meningitis, acute renal failure, urination issues.

Mild side effects

Nausea, indigestion, itching, loss of appetite, vomiting, abdominal pain, dyspepsia, diarrhea, gastrointestinal discomfort, thirst, stomatitis, abdominal bloating, constipation, eczema, petechiae, rashes, itching, visual impairment, hearing loss, tinnitus, taste abnormalities, aseptic meningitis, hypotension, hypertension, palpitations, fatigue, fever, nosebleeds, decreases in hemoglobin and hematocrit values, decreased platelet aggregation, prolonged bleeding time.

This medication may be sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is recommended to store the medication at room temperature, ideally between 15 degrees and 25 degrees Celsius.

Appearance

A white to pale yellow opaque syrup in a distinctive smelling white bottle.

Package unit

500mL/bottle