Coxib Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or take 100 mg twice daily in divided doses. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication can cause serious side effects such as gastrointestinal bleeding in individuals who regularly consume three or more alcoholic drinks a day; therefore, consultation with a doctor or pharmacist is mandatory. This medication may increase the risk of cardiovascular problems such as heart attack or stroke, so it should be used for the shortest duration and at the minimal effective dose possible. Due to the risk of ulcers or bleeding in the gastrointestinal tract, special caution is needed for individuals with gastrointestinal diseases, the elderly, or those taking the medication for a long time. Patients with allergic reactions or certain conditions (e.g., severe liver disease, kidney disease, heart failure, active gastric ulcer, etc.) should not take this medication. Individuals with impaired liver or kidney function, asthma, high blood pressure, edema, or a history of cardiovascular disease should use this medication cautiously and require regular checks. This medication can cause various side effects, including indigestion, headache, dizziness, skin rash, high blood pressure, gastrointestinal bleeding, etc. If any abnormal symptoms occur, immediate consultation with a doctor is required. Women who are pregnant or might be pregnant, and those who are breastfeeding should not use this medication, and women planning to become pregnant should consult a doctor before taking it. This medication may interact with other drugs, so it is crucial to inform the doctor of any other medications being taken, especially when taken with blood pressure medications, diuretics, anticoagulants, and antidepressants. Dizziness or drowsiness may occur, so it is advisable to avoid driving or operating machinery after taking this medication. With long-term use, regular blood tests and checks of liver and kidney function are necessary, and treatment may be discontinued if any abnormalities are found. Children and adolescents are advised not to take this medication as its safety and efficacy in this population have not been established. The elderly may have decreased liver, kidney, or heart function, so closer monitoring is necessary when taking this medication.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, indigestion, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual clouding, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, insomnia, loss of appetite, increased appetite, depression, nervous hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, worsening of epilepsy, upper respiratory tract infection, pharyngitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, epistaxis, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitivity reactions, pruritus, erythematous rash, papular rash, skin diseases, skin dryness, increased sweating, erythema multiforme, exfoliative dermatitis, skin mucosal syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, arrhythmia, left ventricular hypertrophy, angina, unstable angina, coronary artery disease, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebrovascular accident, peripheral gangrene, thrombotic phlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, herpes simplex, wound infection, gingivitis, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, mastalgia, menopausal symptoms, fibrocystic breast disease, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urine urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased blood sodium, increased blood potassium, increased BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, increased LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal deformities, myalgia, cervical tension, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, visual clouding, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, ageusia, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, female infertility

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best kept at a temperature between 15 and 30 degrees Celsius to maintain its efficacy.

Appearance

A capsule with a yellow upper part and a white lower part filled with a white to light yellow powder

Package unit

30 capsules/bottle, 300 capsules/bottle