Sinobafin Tablet 10 mg (Amlodipine Besylate)

Adult dose

Administer 5 mg orally once daily as amlodipine, with the possibility to increase to a maximum of 10 mg daily based on patient response. Adjust according to age and symptoms.

This medication should not be used by certain patients. It may be dangerous for individuals allergic to this drug or similar drugs, those who are breastfeeding, individuals with severely impaired liver function, those with severely narrowed heart valves, and those in a state of shock. Patients with severe hypotension, those requiring renal dialysis, elderly patients, pregnant women or women of childbearing age should use this medication with caution. Common side effects may include flushing, fatigue, edema, palpitations, dizziness, headache, drowsiness, abdominal pain, nausea. Rarely, varied adverse reactions such as lethargy, decreased blood pressure, sensory disturbances, erectile dysfunction, dry mouth, hyperglycemia, joint pain, skin rashes may occur, necessitating consultation with a physician upon occurrence of unusual symptoms. Heart failure patients may exhibit symptoms of pulmonary edema with long-term use of this medication, so caution is required. Patients with liver dysfunction may experience prolonged drug effects, requiring dosage adjustments and careful monitoring. This drug lowers blood pressure gradually and is not suitable for situations where rapid blood pressure reduction is needed. While it has minimal impact on driving or operating machinery, care should be taken if dizziness occurs. This drug may interact with several other medications; particularly, the combination with grapefruit juice may enhance blood pressure lowering effects, so it is advisable to avoid concurrent use. The risk of hypotension may increase when combined with certain drugs, so patients should inform healthcare professionals of all medications they are taking. Safety during pregnancy has not been established, so it should only be used during pregnancy when truly necessary, and it is recommended to stop breastfeeding when taking this medication. Effectiveness has been confirmed in children aged 6 and older, but it is not to be used in children under 6 years of age. Overdose can cause severe hypotension and cardiac problems, requiring immediate emergency treatment, and this medication is not removed by dialysis, so prompt medical action is crucial.

Serious side effects

• Hives
• toxic epidermal necrolysis
• jaundice
• hepatitis
• severe edema
• severe allergic reactions
• liver dysfunction
• severe skin reactions.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• lethargy

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain storage at room temperature between 1 to 30 degrees Celsius.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle