Bonel Tablet 150 mg (Risedronate Sodium Hydrate)

Adult dose

1. Adults : Administer 150 mg of risedronate sodium orally once a month. 2. Older adults : No dose adjustment is necessary because the bioavailability and pharmacodynamics of this medicine in older adults (over 60 years) are similar to those in younger people. 4. Patients with renal impairment : No dose adjustment is necessary in patients with creatinine clearance of 30 mL/min or greater. This medicine is contraindicated in patients with severe renal impairment and creatinine clearance below 30 mL/min. ○ Food interferes with the absorption of this medicine. For adequate absorption, take it at least 30 minutes before the first food or beverage other than water of the day. To help this medicine reach the stomach easily and reduce the possibility of esophageal irritation, take it in an upright position with a sufficient amount of plain water (170 ∼ 230 mL). Taking it with other beverages, including mineral water, may reduce absorption. Do not chew or suck this medicine because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. ○ If a patient forgets to take a dose on the scheduled dosing day, follow these instructions. - If the next scheduled dosing day is 7 days or more away, take 1 tablet the next morning after remembering. Take the next dose again on the originally scheduled dosing day. Do not take more than 1 tablet of this medicine within 7 days. - If the next scheduled dosing day is within 7 days, wait until the originally scheduled dosing day and then take 1 tablet of this medicine.

Child dose

3. Children : Safety and efficacy have not been established in children under 18 years.

This medication can irritate the upper gastrointestinal mucosa, so patients with esophageal diseases, gastritis, or ulcers should be cautious when taking it. After taking the medication, it should always be taken with a sufficient amount of water, and lying down for more than 30 minutes afterward should be avoided to prevent esophageal irritation. If symptoms such as pain in the esophagus, difficulty swallowing, or heartburn appear, stop taking the medication immediately and consult a doctor. Patients with esophageal motility disorders, hypocalcemia, pregnant or breastfeeding women, and those with severe renal impairment should not take this medication. If calcium and vitamin D are deficient, they should be supplemented beforehand, and care should be taken not to take other medications containing calcium or magnesium along with this drug, as they may interfere with absorption. Rare side effects such as osteonecrosis of the jaw may occur, so consulting a doctor before dental treatment is important. Long-term use may increase the risk of atypical fractures, so if there is pain in the legs or groin, a doctor's examination is required. Safety and efficacy have not been established for children and adolescents under 18 years, so it is advisable not to use it. Elderly patients can generally use it safely, but caution is needed when taking it. Overdose may result in hypocalcemia; if symptoms occur, immediate medical attention is required. This medication should be kept out of the reach of children and it is advisable not to transfer it to other containers.

• Esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• low back pain
• accidental injury
• pain

This medication should be stored in a tightly sealed container to prevent air exposure, and it is advisable to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance

Light blue elliptical film-coated tablet

Package unit

1 tablet (1 tablet/PTP X 1)