Risnel Tablet 150 mg (Risedronate Sodium Hydrate)

Adult dose

1. Adults : Administer risedronate sodium 150 mg orally once a month. 2. Older adults : No dose adjustment is necessary because the bioavailability and pharmacodynamics of this medicine in older adults (over 60 years) are similar to those in younger people. 4. Patients with renal impairment : No dose adjustment is necessary in patients with a creatinine clearance of 30 mL/min or higher. This medicine is contraindicated in patients with severe renal impairment and a creatinine clearance below 30 mL/min. ○ Food interferes with the absorption of this medicine. For adequate absorption, take it at least 30 minutes before the first food or beverage other than water of the day. To help this medicine reach the stomach easily and reduce the possibility of esophageal irritation, take it in an upright position with a sufficient amount of plain water (170 ∼ 230 mL). Taking it with other beverages, including mineral water, may reduce absorption. Do not chew or suck this medicine because of the possibility of oropharyngeal ulceration. Do not lie down for at least 30 minutes after taking it. ○ If a patient forgets to take this medicine on the scheduled day, follow these instructions. - If the next scheduled dose is 7 days or more away, take 1 tablet the morning after remembering. Take the next dose on the originally scheduled day. Do not take more than 1 tablet of this medicine within 7 days. - If the next scheduled dose is less than 7 days away, wait until the originally scheduled day and then take 1 tablet.

Child dose

3. Children : The safety and efficacy of this medicine in children under 18 years of age have not been established.

This medication may irritate the mucous membranes of the stomach and esophagus, so caution is needed for individuals with upper gastrointestinal diseases such as gastritis, esophagitis, or esophageal ulcers. Especially, patients with Barrett's esophagus or dysphagia must consult a doctor before taking this medication. Take this medication with a sufficient amount of water (170-230 mL), and do not lie down for at least 30 minutes after taking it. Due to the potential for esophageal irritation, if symptoms such as dysphagia, pain behind the sternum, or heartburn occur after taking this medication, discontinue use immediately and consult a doctor. This medication is contraindicated for patients with esophageal stricture or achalasia causing delayed esophageal transit, patients with hypocalcemia, pregnant and nursing women, and those with severe renal impairment. Patients allergic to the colors included in this medication should also be cautious. Before taking this medication, you must treat bone and mineral metabolism disorders such as hypocalcemia or vitamin D deficiency, and it is important to ensure adequate intake of calcium and vitamin D. The absorption of this medication may be impaired when taken with drugs or foods that contain calcium, magnesium, iron, aluminum, etc.; therefore, maintain an interval of administration. Rarely, serious side effects such as jaw necrosis or atypical femoral fractures may occur with long-term use, necessitating regular check-ups and caution. The safety for children has not been established, and it can be used in elderly patients without special dose adjustments. In cases of overdose, serum calcium and phosphorus levels may decrease, so if symptoms of hypocalcemia appear, visit a medical institution immediately. This medication should be kept out of the reach of children, and it is advisable not to transfer it to another container.

• esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• back pain
• accidental injury
• pain

This medication should be stored in a tightly closed container to prevent air entry, preferably at room temperature between 1°C and 30°C. Storing it this way helps maintain the effectiveness of the medication for longer.

Appearance

Bright blue rectangular film-coated tablet

Package unit

1 tablet/PTP