Cresant 20 mg (Rosuvastatin Calcium)

Adult dosage

For adults with primary hypercholesterolemia, combined hyperlipidemia, etc., the medication can be taken once daily at any time regardless of meals. The initial dose is 5 mg, and if necessary, it can be increased to 10 mg at intervals of at least 4 weeks based on treatment goals. The maximum daily dose can go up to 20 mg.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), the dosage is individually adjusted within the range of 5 mg to 20 mg once daily. Dosage adjustments are made at intervals of at least 4 weeks.

This medication should not be administered to certain patients. For example, those who are allergic to any components of this drug, have severely impaired liver function, have muscle disorders, have severely impaired kidney function, or are pregnant or breastfeeding should not use this medication. Additionally, high doses are prohibited for patients at high risk for muscle disorders. This medication contains lactose, so caution is needed for those with lactose intolerance. This medication should be used cautiously in patients with impaired liver function or those who consume large amounts of alcohol, and regular liver function tests should be conducted. If symptoms such as muscle pain or weakness occur, the doctor should be informed immediately, and in severe cases, the medication should be discontinued. Furthermore, this medication may need to be discontinued in severe disease states. This drug can rarely cause serious skin reactions, liver damage, or muscle damage, so if any unusual symptoms occur, immediate consultation with healthcare professionals is necessary. Interactions may occur when taken with other medications; therefore, it is essential to inform the prescribing physician if other medications are being taken, especially certain antiviral agents, immunosuppressants, antibiotics, and fibrates. Women who are pregnant or planning to become pregnant should not use this medication and should utilize appropriate contraception. Breastfeeding mothers should also avoid taking this medication. In case of overdose, there is no specific antidote, so symptomatic treatment and tests on liver function and muscle enzymes may be necessary. Dizziness may occur when driving or operating machinery, so caution is needed. This medication may show higher concentrations in Asians, so dose adjustment may be required. Regular blood tests and observation of symptoms should be conducted during the use of this medication for safe administration.

Serious side effects

Hives, angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), hepatitis, jaundice, liver failure, severe muscle weakness, rhabdomyolysis, immune-mediated necrotizing myopathy, thrombocytopenia, peripheral neuropathy, memory loss, peripheral nerve damage, dyspnea, severe skin adverse reactions, severe allergic reactions, severe edema, urinary abnormalities, severe neurological symptoms (headache, seizures).

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, myalgia, weakness, thrombocytopenia, diarrhea, visual disturbances (ocular muscle weakness), sensory disturbances, chest discomfort, anorexia, abdominal bloating, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, fatigue.

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is best to store the medication at room temperature between 1°C and 30°C.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)], 100 tablets/box [(10 tablets/PTP x 10)], 30 tablets/bottle, 100 tablets/bottle