Krestin Tablets 10 mg (Rosuvastatin Calcium)

Adult dosage

It can be administered at any time during the day regardless of meals. The initial dose is 5 mg once daily, and it can be adjusted to a maintenance dose. The maintenance dose is usually adjusted to 10 mg once daily for most patients. The maintenance dose should be adjusted appropriately based on LDL-cholesterol level, treatment goals, and patient response at intervals of 4 weeks or more, and can be increased up to a maximum of 20 mg per day.

Children's dosage

The usual dosage range is 5 mg to 20 mg once daily. The administration dose should be adjusted according to the therapeutic goal of each individual patient and can be modified at intervals of 4 weeks or more. For children under 10 years old, the safety and efficacy have not been established.

This medication should not be administered to certain patients. For example, it should not be used in patients who are allergic to it, patients with severely impaired liver function, patients with muscle disorders, patients taking certain medications, and patients with severe kidney dysfunction. Additionally, it should be used cautiously in pregnant or breastfeeding women, and in fertile women who are not using adequate contraception. Patients at high risk for muscle-related side effects, such as those with hypothyroidism or a history of genetic muscle disorders, should be monitored closely, particularly at high doses. This medication contains lactose, so it should not be administered to patients with lactose intolerance or related genetic conditions. It is important to regularly monitor liver function and muscle condition during treatment with this medication. If symptoms such as myalgia, muscle weakness, fatigue, or fever occur, patients should immediately inform their healthcare provider, and if necessary, discontinue use. Patients who consume alcohol excessively or have a history of liver disease should undergo liver function testing before taking this medication and be monitored closely. This medication may interact with other drugs, so it is essential to inform the healthcare provider of any other medications being taken. Pregnant or breastfeeding women should avoid using this medication as it may pose risks to the fetus or baby, so they should ensure contraception or refrain from use. In the event of an overdose, there is no specific antidote, so treatment should be tailored to symptoms, and liver function and muscle enzyme levels should be monitored. Dizziness may occur while taking this medication, so caution is advised when driving or operating machinery. Finally, if serious skin reactions occur while taking this medication, it should be discontinued immediately, and the healthcare provider should be consulted.

Serious side effects

Allergic reactions including urticaria and angioedema, pancreatitis, muscle disorders, rhabdomyolysis, severe muscle weakness, oculomotor muscle weakness, jaundice, hepatitis, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, acute kidney failure, oliguria, chest tightness, shortness of breath, severe edema

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication should be stored in a tightly sealed container to protect it from air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

28 tablets PTP