Crestin Tablet 10 mg (Rosuvastatin Calcium)

Adult dose

Regardless of meals, dosages start at 5 mg once daily at any time during the day. If necessary, the maintenance dosage can be adjusted to 10 mg once daily at intervals of 4 weeks or more, with a maximum of 20 mg daily.

Child dose

Children aged 10 to 17 years should receive 5 mg to 20 mg once daily, with the dosage adjusted individually at intervals of 4 weeks or more according to the treatment goals. For children under 10 years, the safety and efficacy have not been established.

This medication should not be used in certain patients. For example, individuals allergic to any of this medication's components, those with severely impaired liver function, those with muscle diseases, and those with significantly reduced kidney function should not take it. Pregnant or breastfeeding women should avoid using this medication, and women of childbearing age should employ appropriate contraception to reduce the possibility of pregnancy. Additionally, individuals at high risk of muscle disease should avoid high dosages of this medication. This medication may affect liver function; therefore, individuals who consume alcohol heavily or have a history of liver disease need to exercise caution and undergo regular liver function tests before and during treatment. If symptoms such as muscle pain or weakness occur, healthcare personnel should be notified immediately, and the medication may need to be discontinued if necessary. Elderly patients or those with renal impairment should be particularly vigilant about muscle-related side effects. This medication can interact with other drugs, so anyone taking other medications must inform their physician or pharmacist. When used with certain drugs, the blood concentration of this medication may increase, raising the risk of side effects. Use during pregnancy may pose a risk to the fetus, so this medication should not be taken if planning for pregnancy or if already pregnant. During lactation, this medication may pass into breast milk, so it is advisable to avoid its use. In cases of overdose, since there is no specific antidote, treatment should be symptom-based along with liver function and muscle enzyme testing. Lastly, this medication may cause dizziness; therefore, caution is advised when driving or operating machinery.

Serious side effects

Allergic reactions including urticaria and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, severe allergic reactions, severe skin reactions, severe muscle weakness, ocular myasthenia gravis, rhabdomyolysis, acute renal failure, oliguria, chest tightness, difficulty breathing, dyspnea, severe cutaneous adverse reactions, severe liver damage, fatal and non-fatal liver failure, severe

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• chest pain

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius to preserve the medication's effectiveness and safety for a prolonged period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle