Medication info
Candesartan Cilexetil 16 mg Tablets

Candesartan Cilexetil 16 mg Tablets

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tablet
Manufacturer / importer
신풍제약(주)
Appearance
A round tablet that is convex on both sides, with a cloudy yellow-pink color
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200907782 · Notified 2009.10.29 · Insurance code 648506240

Summary

Main use
Improvement of essential hypertension and heart failure (left ventricular function impairment)
Who takes it
Adults · Children
Adult dose
For essential hypertension, the initial and maintenance dose for adults is recommended to be 8 to 16 mg of Candesartan Cilexetil orally once daily. If blood pressure is not adequately controlled after 4 weeks of treatment at a dose of 16 mg once daily, it may be increased to a maximum of 32 mg once daily. The maximum effect is usually observed within 4 weeks of starting treatment. Patients with intravascular volume depletion or kidney dysfunction should receive an initial dose of 4 mg. For liver dysfunction,
Child dose
The safety and efficacy of this medication have not been established in adolescents and children under the age of 18.

Ingredients

Manufacturer
신풍제약(주)

Efficacy & effects

Improvement of essential hypertension and heart failure (left ventricular function impairment)

  • Essential hypertension
  • heart failure
  • impaired left ventricular systolic function
  • decreased left ventricular ejection fraction
View approved original text

This medication is used to control blood pressure in patients with essential hypertension. It also effectively alleviates symptoms in heart failure patients with impaired left ventricular systolic function, especially those who are intolerant to ACE inhibitors or who require additional treatment. Therefore, it helps to manage both heart failure and hypertension simultaneously.

How to take

Adult dose

For essential hypertension, the initial and maintenance dose for adults is recommended to be 8 to 16 mg of Candesartan Cilexetil orally once daily. If blood pressure is not adequately controlled after 4 weeks of treatment at a dose of 16 mg once daily, it may be increased to a maximum of 32 mg once daily. The maximum effect is usually observed within 4 weeks of starting treatment. Patients with intravascular volume depletion or kidney dysfunction should receive an initial dose of 4 mg. For liver dysfunction,

Child dose

The safety and efficacy of this medication have not been established in adolescents and children under the age of 18.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially after the second trimester, so it must be discontinued immediately if pregnancy is confirmed. It should not be administered to those allergic to this medication or its components, pregnant women or women who may become pregnant, nursing mothers, and patients with severe liver dysfunction or cholestasis. Additionally, patients with hereditary angioedema, a history of angioedema while taking ACE inhibitors or angiotensin II receptor antagonists, patients with primary hyperaldosteronism, and those with lactose intolerance should not take this medication. Elderly patients, those with hyperkalemia, liver disease, valve heart disease, cardiovascular diseases, and those with impaired kidney function should take this medication with caution, and regularly monitor blood pressure, kidney function, and serum potassium levels. This medication may cause side effects such as dizziness, back pain, and respiratory infections; rarely, serious allergic reactions or worsening of kidney function, blood disorders, etc., may occur, so if any unusual symptoms appear, consult a doctor immediately. Due to the strong hypotensive effect, risks of hypotension, syncope, and renal dysfunction may occur, thus especially patients undergoing dialysis or on strict salt restrictions, as well as those on diuretics, should start with a small dose and gradually increase. Caution is required when driving or operating machinery because transient dizziness or drowsiness may occur. When taking other antihypertensives, diuretics, or potassium-sparing diuretics, interactions may increase side effects, so it is necessary to consult a physician. Pregnant and nursing women are advised not to take this medication, and if it is absolutely necessary to take it, must strictly follow the physician’s instructions. The safety of this drug in children and adolescents under the age of 18 has not been established, so its use is not recommended. In case of overdose, symptoms such as hypotension, dizziness, and tachycardia may arise; immediate hospital attention is required for proper treatment. This medication should be kept out of reach of children, and transferring it to another container is not advisable for maintaining quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, cough with fever, yellowness of the skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, vision problems, paralysis, urination

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infection, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, joint pain, proteinuria, weakness, fever, paresthesia, dyspepsia, gastritis, tachycardia, palpitations, increased creatine kinase (CK), hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, shortness of breath, rash,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

A round tablet that is convex on both sides, with a cloudy yellow-pink color

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.