Difenplast (Diclofenac Sodium)

Adult dosage

For adults (15 years and older), apply 1 patch once daily to the affected area.

This medication should not be used by anyone who has previously experienced allergic reactions to this drug or its components. Those who have experienced asthma attacks due to aspirin or other non-steroidal anti-inflammatory drugs should be cautious when using this medication as it can pose a risk of severe asthma attacks. It is advisable not to use this medication for children under 15 years of age as its safety has not been sufficiently proven. It should not be used during the last 3 months of pregnancy, as it can have serious effects on the fetus and mother. Co-administration with other anti-inflammatory drugs containing similar components may increase the risk of side effects; therefore, it should not be taken together. Patients with bronchial asthma, suspected skin infections, or chronic diseases should consult a doctor or pharmacist before using this medication. During the early and middle stages of pregnancy, the impact of this medication on the fetus is not clear, so it should only be used when necessary for the minimum duration and dosage. Breastfeeding women should refrain from using this medication as it may pass into breast milk. Elderly patients should take this medication very cautiously, as there is an increased risk of cardiovascular, gastrointestinal, and renal issues. They should monitor for any abnormal symptoms. If severe rashes, red spots, blisters, or itching occur on the skin during the use of this medication, it should be discontinued immediately, and consultation with a doctor or pharmacist is advised. While this medication helps alleviate symptoms, it does not treat the underlying cause, so caution is needed for long-term use. After 2 weeks of use, the effects and side effects should be reassessed, and it should not be applied to the eyes, mucous membranes, or damaged skin. Caution should be exercised as temporary irritation or tingling may occur if there is skin damage. There is a risk of seizures when used with certain antibiotics, and any abnormal symptoms should be reported to a healthcare provider immediately. Overdose may cause low blood pressure, decreased kidney function, seizures, and gastrointestinal discomfort, so the prescribed dosage should be strictly adhered to. This medication may affect kidney function, so renal status should be closely monitored when used with diuretics or blood pressure medications. This medication can increase the risk of gastrointestinal bleeding or ulcers, so extra caution is required when taken with drugs that may pose a bleeding risk. Store this medication in a cool, dry place out of the reach of children, and keep it in its original container.

Serious side effects

• Hives
• severe swelling (including angioedema)
• chest tightness
• difficulty breathing
• asthma attacks
• severe rashes accompanied by high fever
• blisters
• skin sloughing
• pain in oral/eye mucosa
• jaundice of the skin or eyes

Mild side effects

Skin irritation, tingling sensation, eczema, dry skin, itching, hyperemia, skin roughness, pain, blisters, pigmentation, gastrointestinal discomfort, low blood pressure, seizures, increased risk of gastrointestinal bleeding, increased risk of gastrointestinal ulcers, increased risk of gastrointestinal perforation

Drug interactions

This medication should not be applied topically or taken with diclofenac preparations or non-steroidal anti-inflammatory drugs (anti-inflammatories). Consult a doctor or pharmacist when used with fluoroquinolone antimicrobial agents, loop diuretics, thiazide diuretics, drugs that interfere with clotting, anti-platelet drugs, selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors.

This medication is sensitive to light and should be stored in a light-blocking, airtight container. It is also recommended to keep the medication at room temperature, maintaining a temperature between 1 and 30 degrees Celsius.

Appearance

This is a transdermal patch that is coated with a colorless to slightly yellowish adhesive substance on a carrier and covered with a solid dressing on a solid surface.

Package unit

(1 prescription) 7 patches/pack, 10 patches/pack (2 prescriptions) 20 patches/pack (3 prescriptions) 4 patches/pack