New Pio Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is administered orally once daily regardless of meals. 1. Monotherapy: Start with 15 mg once daily, and may increase to 30 mg once daily if the effect is insufficient. 2. Combination therapy: - Sulfonylurea: Administer 15 mg once daily - Metformin: Administer 15 mg once daily - Insulin: Administer 15 mg once daily The maximum recommended dose is 30 mg once daily.

Child dose

There is no experience with patients under 18 years of age, and use is not recommended.

This medication is used for the treatment of type 2 diabetes and helps in the action of insulin. It may place additional strain on the heart during use, so patients with congestive heart failure or a history of congestive heart failure should not take it. During the initial dosage or after increasing the dose, carefully observe for sudden weight gain, shortness of breath, and swelling. If these symptoms occur, consult a physician immediately for appropriate treatment, and if necessary, discontinue or reduce the dosage. This medication may cause fluid retention leading to swelling, and caution is especially needed for patients with heart disease. Patients with active bladder cancer or a history of bladder cancer should not take this medication. Patients with severely impaired liver or kidney function should also avoid using this medication. Women who are pregnant or may become pregnant should not use this medication, and premenopausal women should employ appropriate contraceptive methods as the risk of pregnancy may increase while taking this medication. Hypoglycemic symptoms may occur when taken with other hypoglycemic agents, so caution is advised, and dosage adjustments for other medications may be necessary. Regular monitoring of blood sugar and liver function tests is required during the use of this medication, and any unusual symptoms such as weight changes, swelling, or shortness of breath should be reported to a physician. Furthermore, long-term use of this medication may lead to weight gain and increased risk of fractures, so consistent management is necessary. Acute overdose may not present any specific symptoms; however, if unusual symptoms occur, consult healthcare professionals immediately. Lastly, this medication has not established safety and efficacy for use in children or adolescents under 18 years of age, so it should not be used.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight changes, shortness of breath, swelling), severe edema, elevated blood pressure, severe allergic reactions (urticaria), severe skin reactions (serious rash accompanied by fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes), respiratory issues (difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever), liver issues (yellowing of the skin or eyes)

Mild side effects

• Headache
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• upper respiratory tract infection
• hypoglycemia
• urinary tract infection
• back pain

This medication should be stored in a container that is protected from light and air, avoiding humid areas, and kept at a temperature between 15 to 30 degrees Celsius. Storing it this way will help maintain its efficacy over time.

Appearance

White to off-white round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle