Japfen Soft Capsule 300 mg (Dexibuprofen)

Adult dosage

Administer 300 mg of dexibuprofen orally, 2 to 4 times daily. However, do not exceed 1,200 mg of dexibuprofen per day.

This medication may cause gastric bleeding if taken by individuals who regularly consume more than 3 alcoholic beverages per day, so it is important to consult a doctor or pharmacist. Caution is advised for patients with a history or risk factors for cardiovascular disease since this medication can increase the risk of cardiovascular problems. If cardiovascular symptoms appear, seek medical advice immediately. This medication may cause serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforation, particularly in the elderly or patients with a history of gastrointestinal issues. Patients with specific diseases such as gastrointestinal ulcers, bleeding, severe blood disorders, liver disorders, kidney disorders, heart failure, hypertension, and those with a history of allergic reactions or asthma should not take this medication. The risk of side effects may increase if this medication is taken with aspirin or other non-steroidal anti-inflammatory drugs, so it is recommended not to take them together. During treatment, breastfeeding should be discontinued, and caution is advised when driving or operating machinery due to possible dizziness or fatigue. Patients with existing conditions such as blood disorders, liver disorders, kidney disorders, hypertension, heart failure, elderly individuals, children, and pregnant women should consult a specialist before taking this medication. If severe allergic reactions, skin rashes, gastrointestinal symptoms, liver dysfunction, kidney issues, or cardiovascular symptoms occur, discontinue use immediately and consult a healthcare provider. This medication should be used at the minimum effective dose for the shortest possible duration, and patients with chronic conditions should undergo regular blood tests and liver/kidney function tests. Caution is required when using after 20 weeks of pregnancy as it may affect fetal kidney function, and in case of overdose, seek immediate medical treatment. This medication should be stored in a cool, dry place out of reach of children and protected from direct sunlight.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin shedding, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, cough with fever-related respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, lightning headache, seizures, altered consciousness, visual abnormalities, paralysis, urination

Mild side effects

• Dyspepsia
• abdominal distension
• heartburn
• upper abdominal pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication concurrently with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate. Additionally, avoid taking corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants, baclofen, immunosuppressants, thrombolytics, ticlopidine, anticoagulants, or agents that affect blood potassium levels.

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius to safely preserve its effectiveness.

Appearance

An orange transparent oval soft capsule containing a pale yellow to light orange transparent viscous liquid.

Package unit

10 capsules/PTP