Korea Candesartan Plus Tablets (Candesartan Cilexetil, Hydrochlorothiazide)

Adult dose

The recommended dose of this medication is 1 tablet once daily, taken regardless of meals. For adults, the dosage of Candesartan Cilexetil should be adjusted before administration, and direct switching from monotherapy to this medication can be considered when clinically appropriate. In patients with decreased effective intravascular blood volume and renal impairment, the initial dose of Candesartan Cilexetil should be adjusted. This medication is not to be administered to patients with severe renal impairment or severe liver impairment.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Do not take this medication if you have an allergic reaction to any of its components or if you have specific kidney and liver diseases, gout, electrolyte imbalance, etc. Patients with excessively low blood pressure or issues with fluid and electrolyte balance, patients with liver disease at risk of hepatic coma, and patients with heart valve disease should use this medication with caution. The Hydrochlorothiazide component may make the skin sensitive to sunlight, so it is important to limit sun exposure and take protective measures to reduce the risk of skin cancer. This medication has a blood pressure-lowering effect, which may cause side effects such as dizziness, headaches, nausea, and fatigue. If these symptoms are severe, consult a physician. While taking this medication, regular blood tests to monitor electrolytes, kidney function, liver function, etc., should be performed, paying particular attention to changes in potassium levels. When taking this medication in conjunction with other antihypertensives, diuretics, potassium supplements, non-steroidal anti-inflammatory drugs, etc., it is essential to inform healthcare professionals due to the potential for interactions. This medication is not recommended for breastfeeding women; if necessary, breastfeeding should be discontinued. Safety in children or adolescents under the age of 18 has not been established, so caution is advised. Elderly patients may have weakened heart and kidney function; therefore, closer monitoring is required when using this medication. In case of overdose, symptoms such as hypotension, dizziness, and electrolyte imbalance may occur, prompting an immediate visit to a medical institution for appropriate treatment. This medication should be kept out of the reach of children and stored in its original container to maintain quality and prevent misuse. Caution is needed when driving or operating machinery, as dizziness or fatigue may occur.

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, high fever with severe rash, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), severe lethargy, liver abnormalities (jaundice), sudden and severe headaches, lightning-like.

Mild side effects

• Headache
• back pain
• dizziness
• respiratory infections
• symptoms resembling influenza
• sinusitis
• bronchitis
• urinary tract infections
• nausea
• bruising

This medication should be stored in a well-sealed container to prevent air or moisture ingress, preferably in a cool place at or below 30 degrees Celsius. Proper storage can maintain the drug's efficacy for an extended period.

Appearance

Biconvex, pale pink, rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle