Medication info
Candesartan Plus Tablet

Candesartan Plus Tablet

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
신풍제약(주)
Appearance
Biconvex light pink rectangular tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200904235 · Notified 2009.06.17 · Insurance code 648504990

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dose of this medication is one tablet once daily, taken regardless of meals. For adults, the dose of candesartan cilexetil should be adjusted before switching to this medication, and the antihypertensive effect is usually observed within four weeks after starting treatment. For the elderly, specific dose adjustments are not necessary. In patients with reduced effective intravascular blood volume and renal impairment (mild to moderate), dose adjustments of candesartan cilexetil are recommended.

Ingredients

Manufacturer
신풍제약(주)

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

Essential hypertension is a condition where blood pressure remains persistently high, which may be difficult to manage with a single medication. This medicine works with multiple components to effectively lower blood pressure and reduce the risk of complications arising from hypertension. It helps to manage blood pressure stably through combination therapy. Therefore, it is used for the treatment of essential hypertension.

How to take

Adult dose

The recommended dose of this medication is one tablet once daily, taken regardless of meals. For adults, the dose of candesartan cilexetil should be adjusted before switching to this medication, and the antihypertensive effect is usually observed within four weeks after starting treatment. For the elderly, specific dose adjustments are not necessary. In patients with reduced effective intravascular blood volume and renal impairment (mild to moderate), dose adjustments of candesartan cilexetil are recommended.

Precautions

This drug can cause serious harm or even death to the fetus and newborn, especially during the second and third trimesters of pregnancy, so it must be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this drug's ingredients or sulfonamide derivatives, pregnant women or those planning a pregnancy, nursing mothers, those with severe renal or hepatic dysfunction, etc., should not take this medication. Patients with excessively low blood pressure or issues regarding fluid and electrolyte balance, certain heart conditions, gout, the elderly, etc. should use this medication cautiously, and it is important to consult a physician before taking it. During treatment, blood pressure, renal function, electrolyte levels, etc. should be monitored regularly to closely observe for adverse reactions or side effects. The hydrochlorothiazide component may lower potassium levels in the body, so potassium levels should be carefully monitored when combined with potassium supplements or potassium-sparing diuretics. This drug may interact with other antihypertensive agents, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), etc., so it is essential to inform healthcare providers of any other medications being taken. The hydrochlorothiazide component can react sensitively to sunlight, potentially increasing the risk of skin cancer, so it is important to avoid sun exposure and pay attention to sun protection during treatment. This drug can pass into breast milk, so nursing mothers should avoid taking it or discontinue breastfeeding, and the safety of this medication for children and adolescents under 18 years has not been established. In case of overdose, symptoms may include low blood pressure, dizziness, electrolyte imbalances, etc., so if symptoms occur, consult a medical professional immediately for appropriate treatment. Finally, this drug should be kept out of reach of children and stored in its original container to prevent quality degradation or misuse.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe liver impairment associated jaundice, elevated liver enzymes, liver dysfunction, hepatitis, acute respiratory distress syndrome, dyspnea, severe allergic reactions, bowel vascular edema, angioedema, acute closed-angle glaucoma, acute myopia, choroidal effusion, severe skin adverse reactions (severe rashes, blisters, skin peeling, mucosal pain), headache (sudden onset).

Mild side effects

Headache, back pain, dizziness, respiratory infections, symptoms similar to influenza, sinusitis, bronchitis, urinary tract infections, nausea, bruising, tachycardia, fatigue, abdominal pain, pharyngitis, dyslipidemia, nasopharyngitis, cough, weakness, fever, diarrhea, loss of appetite, gastrointestinal irritation, constipation, muscle pain, otalgia, hyperglycemia, hyperuricemia, electrolyte imbalances (hyponatremia, hypokalemia, etc.), orthostatic hypotension, sleep disturbances, depression.

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly sealed container to protect it from air or moisture, and it is recommended to keep it at a cool temperature below 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness over time.

Appearance and packaging

Appearance

Biconvex light pink rectangular tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.