NAP Tablet (Naproxen Sodium)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis Adults may take 275-550 mg of Naproxen Sodium orally twice a day (every 12 hours). 2. Acute gout As an initial dose, adults may take 825 mg of Naproxen Sodium orally, followed by 275 mg orally every 8 hours until the attack resolves. 3. Musculoskeletal disorders, postoperative pain, post-extraction pain

This medication should be taken with caution by individuals who regularly consume more than three drinks a day, as it may increase the risk of gastrointestinal bleeding; it is essential to consult a doctor or pharmacist. Non-steroidal anti-inflammatory drugs including this medication may increase the risk of cardiovascular diseases, so patients with cardiovascular conditions or risk factors should be monitored carefully. Serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforations may occur, particularly in elderly patients or those with a history of gastrointestinal diseases. This medication should not be used by patients with a history of peptic ulcers, serious blood disorders, liver dysfunction, kidney dysfunction, heart failure, hypertension, or allergies to this drug or non-steroidal anti-inflammatory drugs. Patients with a history of peptic ulcers, blood disorders, bleeding tendencies, liver dysfunction, kidney dysfunction, heart function impairment, hypertension, hypersensitivity, asthma, autoimmune diseases, and elderly patients should be administered this medication with caution. Various side effects such as allergic reactions, gastrointestinal bleeding, blood disorders, liver dysfunction, kidney dysfunction, neurological disorders, and skin rashes may occur; any unusual symptoms should be reported to a doctor immediately. This medication should be used at the lowest effective dose for the shortest duration necessary, and patients with chronic diseases should have regular blood tests and liver and kidney function tests. The risk of side effects increases when combining with other non-steroidal anti-inflammatory drugs, so these should not be taken together, and interactions with specific medications may occur; therefore, inform your doctor of any other medications being taken. It should not be used during the late stages of pregnancy as it may pose risks to the fetus, and caution is needed in the later stages of pregnancy due to potential kidney function impairment and oligohydramnios. Breastfeeding women are advised not to take this medication as it may transmit through breast milk and cause side effects in the newborn. It is preferable not to administer to infants under 2 years due to the lack of established safety, and the minimum effective dose should be carefully administered to children and the elderly. In case of overdose, symptoms like drowsiness, dyspepsia, and vomiting may occur; prompt medical attention is required. Store this medication out of reach of children and do not transfer it to other containers to maintain safety and quality.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, hematemesis, gastrointestinal bleeding, peptic ulcer, perforation, Stevens-Johnson syndrome, epidermal necrolysis, anaphylactic reactions, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy, sudden and very severe headache, seizures,

Mild side effects

• Nausea
• stomach pain
• abdominal pain
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs, naproxen derivatives, aspirin, or high doses of methotrexate. Phenytoin anticonvulsants, sulfonamides, sulfonylurea-based antidiabetic agents, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics, thiazide diuretics, probenecid, lithium, low-dose methotrexate, coumarin anticoagulants (anticoagulants) (warfarin), are not recommended for use together.

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. The storage temperature should be kept between 1 to 30 degrees Celsius in a room temperature environment to maintain its effectiveness and safety for a longer duration.

Appearance

Light blue oval film-coated tablet

Package unit

10 tablets/PTP