Monifil Tablet 350mg (Moniflumate)

Adult dose

Adults: The initial dose is 350 mg of morniflumate twice daily. Depending on the patient, the dose may be increased to a maximum of 700 mg twice daily. It is advisable to start this medicine at a low dose and increase it to the effective dose. Adjust the dose as appropriate according to age and symptoms.

Patients who regularly consume more than three drinks per day should consult with their doctor or pharmacist before taking this medication or other analgesics. This medication may affect the cardiovascular system and increase the risk of heart disease or stroke, so particular caution is advised for individuals with cardiovascular diseases or risk factors. Additionally, this drug can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforations, so those with a history of gastrointestinal disease or older patients should use it more cautiously. Allergic reactions may occur, and severe reactions such as anaphylaxis can happen even in those who have never taken non-steroidal anti-inflammatory drugs. Since this medication may mask inflammatory symptoms and delay the diagnosis of infectious complications, it should be used with antibiotics if infection is suspected. This medication should not be administered to patients with a history of peptic ulcers, gastrointestinal bleeding, severe blood abnormalities, liver impairment, kidney impairment, heart failure, hypertension, drug hypersensitivity, allergy to aspirin or other non-steroidal anti-inflammatory drugs, pregnant or breastfeeding women, children, and infants. Patients with genetic metabolic disorders such as lactose intolerance should also avoid taking it. Particular caution is needed for specific groups of patients, including those with blood abnormalities, bleeding tendencies, liver impairment, kidney impairment, hypersensitivity, heart dysfunction, hypertension, autoimmune diseases, asthma, ulcerative colitis, Crohn's disease, esophageal passage disorders, and the elderly. This medication may cause gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea, and rarely, serious bleeding or ulcers may occur. Various side effects such as skin rashes, liver function abnormalities, kidney dysfunction, blood abnormalities, central nervous system abnormalities, and cardiovascular issues have been reported, so any unusual symptoms should be reported to a physician immediately. This medication should be taken at the lowest effective dose for the shortest duration and regular blood tests, as well as liver and kidney function tests, are recommended during long-term use. Particularly in elderly patients or those with chronic diseases, special attention should be paid to the occurrence of side effects and caution exercised during use. This drug may interact with other non-steroidal anti-inflammatory drugs, glucocorticoids, ACE inhibitors, aspirin, diuretics, lithium, methotrexate, digoxin, anticoagulants, and others, so consulting with a physician is necessary when used in combination. During pregnancy, especially in late pregnancy, it may pose a risk to the fetus, so women who may become pregnant should consult a physician before taking this medication. It is advisable to take this medication after meals with plenty of water, and not to chew the tablets or take them on an empty stomach. Caution should be exercised when driving or operating machinery, as drowsiness or decreased reaction may occur. In case of overdose, emergency measures such as inducing vomiting and gastric lavage are necessary, and if symptoms such as hypotension, kidney failure, or seizures appear, immediate medical attention should be sought. This medication should be stored out of reach of children and care should be taken to avoid transferring it to other containers.

Shock symptoms (chest pain, coldness, difficulty breathing, limb paralysis, low blood pressure, edema, rash, itching), nausea, vomiting, stomach pain, heartburn, diarrhea, bleeding, perforated peptic ulcer, gastrointestinal bleeding (hematemesis, melena, bleeding, diarrhea), esophageal ulcer, loss of appetite, indigestion, black stools, aphthous stomatitis, dry mouth, dry mucous membranes, bloody diarrhea, changes in appetite, pancreatitis, colitis, abdominal cramps, abdominal bloating, discomfort in the stomach region, gastritis, glossitis, esophageal lesions, diaphragmatic intestinal stricture, stomatitis, angular cheilitis, polydipsia, constipation, ulcers of the small and large intestine, lower gastrointestinal disorders (nonspecific hemorrhagic colitis, exacerbation of Crohn's disease or ulcerative colitis), granulocytopenia, decreased hemoglobin, leukopenia, thrombocytopenia, anemia, aplastic anemia, hemolytic anemia, agranulocytosis, bleeding tendency, decreased platelet function, eosinophilia, skin rash, hives, bullous pemphigoid, erythroderma, purpura, allergic purpura, Stevens-Johnson syndrome, Lyell's syndrome, photosensitivity, erythema, itching, eczema, dermatitis, angioedema, erythema multiforme, flushing, exudative dermatitis, hepatitis, hepatitis accompanied by jaundice, jaundice, liver dysfunction, elevated AST, ALT, and ALP, fulminant hepatitis, acute renal failure, interstitial nephritis, renal papillary necrosis, oliguria, hematuria, proteinuria, nephrotic syndrome, elevated serum creatinine, elevated BUN, vasculitis, pneumonia, asthma attack, angioedema, hypotension, anaphylactic systemic reaction, rash, hives, aseptic meningitis, headache, nausea, vomiting, insomnia, stiff neck, fever, consciousness disorder, depression, irritability, anxiety, diplopia, memory impairment, disorientation, nightmares, tremors, psychotic reactions, drowsiness, dizziness, neuroexcitation, paralysis, confusion, hallucinations, convulsions, visual blurring, tinnitus, hearing impairment, taste impairment, transient pain, dry sensation, superficial keratitis, elevated blood pressure, decreased blood pressure, palpitations, tachycardia, congestive heart failure, ventricular extrasystole, myocardial infarction, chest pain, epistaxis, severe asthma attack, pharyngeal edema, interstitial pneumonia, oliguria, hematuria, proteinuria, frequent urination, nocturia, erectile dysfunction, vaginal bleeding, nipple necrosis, rhabdomyolysis, edema, hair loss, general malaise, sweating, fever, chest pain, lip swelling, heartburn, abdominal pain, gastrointestinal disorders, indigestion, nausea, abdominal discomfort, facial swelling, vomiting, gastritis, abdominal bloating, diarrhea, constipation, gastric ulcer, stomatitis, abdominal cramps, gastrointestinal bleeding, weight gain, fever, peripheral edema, headache, dizziness, wheezing, upper respiratory infection, difficulty breathing, palpitations, decreased blood pressure, dysuria, urinary incontinence, increased serum creatinine, elevated BUN, hyperglycemia, hypoglycemia, decreased vision, sense of floating, insomnia

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Cream-colored rectangular tablet

Package unit

30 tablets/bottle, 300 tablets/bottle