Nobask 10 mg (Amlodipine Besilate)

Adult dose

Take 5 mg of amlodipine orally once daily, and the dose may be increased to a maximum of 10 mg daily based on the patient's response. Adjustments should be made according to age and symptoms.

Child dose

The oral dose of amlodipine for effective blood pressure lowering is 2.5 mg-5 mg once daily. Doses exceeding 5 mg per day in pediatric patients have not been studied.

This medication should not be used in certain patients. For example, those who are allergic to this drug or similar drugs, those who are breastfeeding, patients with severely impaired liver function, patients with severe aortic stenosis, and those in shock should not take this medication. Additionally, this medication may require careful use in certain cases. Patients with severe hypotension, those with severely impaired kidney function requiring dialysis, elderly patients, and women who are pregnant or may become pregnant should consult their doctor before taking this medication. Generally, this medication has good tolerability, but symptoms such as flushing, fatigue, swelling, palpitations, dizziness, headaches, drowsiness, abdominal pain, and nausea may occur during use. Rarely, low blood pressure, allergic reactions, skin rashes, and liver function abnormalities have also been reported. Caution is advised for heart failure patients due to the risk of pulmonary edema, and patients with impaired liver function may require dose adjustments as the drug may remain in the body for a long time. This medication takes effect slowly, thus it is not suitable for rapid blood pressure lowering. There may be interactions when taken with other medications. Specifically, taking it with grapefruit juice may lead to excessive blood pressure-lowering effects, thus it is advisable to avoid it. Additionally, when taking it with certain antibiotics or blood pressure medications, analgesics, etc., notify your doctor or pharmacist and observe carefully. The safety of this medication during pregnancy or breastfeeding is not confirmed; therefore, it should only be taken under the discretion of a physician when absolutely necessary, and it is recommended to cease breastfeeding during this time. For children, it is recommended for use only in those aged 6 years and above, as its efficacy and safety have not been established in children under 6 years of age. In cases of overdose, severe hypotension and cardiac dysfunction may occur, necessitating immediate medical attention. This drug is not removed by dialysis, so other treatment methods may be required. Finally, this medication has no risk of carcinogenicity or mutagenicity even with long-term use, and elderly patients can take it at standard dosages.

Serious side effects

Hives, angioedema, toxic epidermal necrolysis, difficulty breathing, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), systemic malaise, hepatitis, jaundice, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, systemic severe edema, hypertension, pulmonary edema, severe hypotension, shock, non-cardiogenic pulmonary edema

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headaches
• drowsiness
• abdominal pain
• nausea
• weakness

Store this medication in a tightly closed container to protect it from air and moisture, and keep it in a cool place between 1 and 25 degrees Celsius. Storing it this way helps maintain the medication's efficacy and prevent deterioration.

Appearance

White octagonal tablet

Package unit

PTP packaging - 28 tablets/box [(14 tablets/blister*2)]