Cardien Tablets 5/10 mg

Adult dose

For Amlodipine (Esamlodipine), take 5 (2.5) mg orally once daily, and the dose may be increased to a maximum of 10 (5) mg daily according to patient response. For Atorvastatin, it starts at 10 mg orally once daily but may be increased to 20 mg or 40 mg once daily if necessary, and it can be administrated within a range of 10 mg to 80 mg once daily, regardless of food.

This medication should not be used in certain patients. For example, those who are allergic to this drug or similar ingredients, have severe liver dysfunction, are pregnant or nursing, or have muscle disorders should not take this drug. Furthermore, those with severe aortic stenosis, in shock, within one month after myocardial infarction, and patients with unstable angina should also refrain from using this medication. Patients with significantly reduced kidney function, the elderly, alcoholics, or those with a history of liver disease should use this drug with caution. Patients likely to exhibit muscle abnormalities should have their muscle enzyme levels checked before taking this medication. During treatment with this drug, side effects such as blood pressure drop, dizziness, headache, fatigue, edema, indigestion, and myalgia may occur, thus caution is necessary. If liver dysfunction or muscle-related symptoms occur, consult a doctor immediately. Pregnant women or those who might become pregnant must ensure adequate contraception when taking this drug, and if pregnancy is confirmed, treatment should be stopped immediately. Nursing women should also avoid this medication and discontinue breastfeeding if necessary. Safety and effectiveness of this drug have not been sufficiently confirmed in children and the elderly, so it should be used cautiously in these age groups. In cases of overdose, severe hypotension or cardiac issues may occur, and immediate medical attention should be sought, as blood dialysis is ineffective for removing this drug. This drug may interact with several other medications, so it is essential to inform the doctor or pharmacist of any other medications being taken. Caution is especially required when combined with medications that affect liver function or cause muscle abnormalities.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, toxic epidermal necrolysis, angioedema, severe allergic reactions, severe skin adverse reactions, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), severe neurological symptoms, significant swelling or urinary abnormalities, jaundice, fulminant hepatitis, hepatitis, cholestatic jaundice, hemorrhagic stroke, rhabdomyolysis, severe muscle weakness, ocular muscle weakness, immune issues.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to keep it at room temperature between 15 to 30 degrees Celsius. This will help maintain the drug's efficacy and prevent degradation.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle