Lozatam Plus Tablets

Adult dose

Start with losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily at 1 tablet. If blood pressure is not controlled after 3 weeks, the dose may be increased to a maximum of losartan potassium 100 mg/hydrochlorothiazide 25 mg once daily at 1 tablet. Other dosage and administration methods for different conditions are detailed, but the principle is to take 1 tablet once daily. For patients with renal impairment (creatinine clearance

Child dose

There is no experience in using this product in children and adolescents (under 18 years old), so the losartan-hydrochlorothiazide combination product is not administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Patients who have had allergic reactions to any ingredients in this medication or to the medication itself, patients with severely impaired kidney or liver function, patients with certain electrolyte imbalances should not take this medication. In some patients, such as those with hypotension, kidney dysfunction, liver disease, gout, and the elderly, this medication should be used with caution, particularly if blood pressure is too low or if there are issues with renal blood vessels. This medication may affect serum potassium levels, so if taken with potassium supplements or other medications containing potassium, the risk of hyperkalemia should be discussed with a physician. Regular monitoring of blood pressure, kidney function, and electrolyte levels is necessary while taking this medication, and healthcare providers should be consulted immediately if any abnormal symptoms arise. Side effects such as dizziness, drowsiness, cough, and skin rash may occur, so caution is necessary when driving or operating machinery. Due to the hydrochlorothiazide component, electrolyte imbalances may occur, and changes in blood sugar and uric acid levels may occur, so caution is particularly necessary for patients with diabetes or gout. This medication may react sensitively to sunlight, so prolonged exposure to ultraviolet light should be avoided, and if any skin abnormalities occur, a physician should be consulted immediately. Women who are pregnant or planning to become pregnant, as well as nursing mothers, must consult with healthcare providers before taking this medication; and breastfeeding or medication may need to be discontinued if necessary. Safety has not been established for use in children or adolescents, so it should not be used in this population. In case of overdose, symptoms such as hypotension and tachycardia may occur, so strict adherence to the dosage is required, and immediate medical attention should be sought if abnormal symptoms occur. This medication should not be taken with grapefruit juice, and the possibility of interactions with other medications should be considered; therefore, patients must inform healthcare providers if they are taking any other medications. This medication should be stored out of reach of children and kept sealed in its original container to prevent misuse or degradation of quality.

Serious side effects

Hives, angioedema (swelling of lips and eyelids and facial rash, swelling of larynx/glottis, swelling of face/lips/pharynx/tongue), severe swelling (edema), cold sweats, pallor, chest tightness, difficulty breathing, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it is important to store it at room temperature, which is between 1 degree and 30 degrees Celsius, to maintain its effectiveness.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets, 300 tablets/bottle