Notobajeng 5mg/10mg

Adult dose

This medication is administered only to adults, and the dosage should be individualized based on the effectiveness and tolerability of each component, amlodipine/atorvastatin, in each patient. Amlodipine (esamlodipine): 5 (2.5) mg is taken orally once daily, and can be increased up to 10 (5) mg daily based on the patient's response. Atorvastatin: 1. For patients with primary hypercholesterolemia and mixed dyslipidemia:

This medication should not be used for certain patients. For example, it should not be administered to patients with a history of allergy or hypersensitivity to this medication, similar types of medications, or its ingredients. It should also not be administered to patients with severely impaired liver function or active liver disease, patients whose serum aminotransferase levels are persistently elevated above three times the normal range, patients with cessation of bile secretion, and patients with muscle disorders. Pregnant women or women who may become pregnant, as well as nursing mothers, should not take this medication. Patients with severe aortic stenosis, shock conditions including cardiogenic shock, severe hypotension, patients within one month after a myocardial infarction, patients with unstable angina, and patients concurrently treated with certain hepatitis medications should also avoid this medication. Additionally, this medication should be used with caution in the following patients: Patients with severe kidney dysfunction or those requiring dialysis, elderly patients, patients with a history of alcoholism or liver disease, patients at high risk of muscle damage, patients with acute heart failure, patients in hypertensive crisis, patients with mild to moderate liver dysfunction, and patients with severe myasthenia gravis, among others. Possible adverse reactions during treatment include facial flushing due to vasodilation, fatigue, edema, palpitations, dizziness, headache, drowsiness, indigestion, myalgia, etc. Rarely, symptoms such as abnormal liver function, allergic reactions, skin rashes, hair loss, and increased sweating have also been reported. Regular liver function tests are required while taking this medication, and if symptoms of liver dysfunction appear, consultation with a doctor should be sought immediately. If symptoms like myalgia, muscle weakness, or weakness appear, they should be reported immediately, and in severe cases, the administration should be discontinued. Pregnant women or those who may become pregnant should not take this medication, and if pregnancy is confirmed during treatment, it should be discontinued immediately and a doctor should be notified. Nursing mothers should also not take this medication. This medication may interact with other drugs, so any other medications being taken should be reported to a doctor or pharmacist. Caution is especially needed when used in combination with medications that affect liver function or increase the risk of muscle damage. In case of overdose, severe hypotension, shock, heart problems, etc. may occur, requiring immediate emergency treatment. This medication should be kept out of reach of children, and it is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), severe allergic reactions, toxic epidermal necrolysis, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory problems, jaundice (yellowing of skin or eyes), liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, severe neurological symptoms, decreased urine output

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to prevent influence from air or moisture. The storage temperature should ideally be maintained between 1 degree and 30 degrees Celsius at room temperature. This helps to maintain the effectiveness of the medication over a long period.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle