Lozatam Plus F Tablets

Adult dose

Losartan Potassium 50 mg/Hydro-chlorothiazide 12.5 mg, one tablet once daily. A dose exceeding Losartan Potassium 100 mg/Hydro-chlorothiazide 25 mg daily is not advisable. If blood pressure is not controlled, the dose may be increased to a maximum of Losartan Potassium 100 mg/Hydro-chlorothiazide 25 mg, one tablet once daily after three weeks of dosing. Creatinine clearance should be above 30 mL/min.

Child dose

There is no experience in using this medication in children and adolescents (under 18 years), so it should not be administered.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this medication or its components, certain kidney diseases, liver disorders, or electrolyte imbalances should not take this medication. Patients with very low blood pressure, impaired kidney function, hyperuricemia or gout, and elderly patients should use this medication with special caution. Dizziness, symptoms of low blood pressure, and electrolyte imbalance symptoms (e.g., muscle cramps, weakness) may occur, and if any unusual symptoms arise, consultation with a physician is necessary. This medication can cause dangerously high levels of potassium in the blood when taken with potassium supplements or medications containing potassium, so potassium supplements should not be taken without consulting a physician. Due to the hydrochlorothiazide component, the skin may become sensitive to sunlight, so care should be taken to use UV protection when going outdoors, and any changes in the skin should be immediately reported to a doctor. This medication may affect kidney and liver function, so regular blood tests and kidney function tests are required, and if any abnormal findings are noted, consultation with a physician is necessary. Caution is advised while driving or operating machinery as dizziness or drowsiness may occur. It is important to regularly check blood pressure and electrolyte levels as directed by a physician while taking this medication. There is no experience in using this drug in children or adolescents, so it should not be administered to them. Store out of reach of children and keep tightly closed in the original container.

Serious side effects

Urticaria, angioedema (swelling of the lips and eyelids and facial rash), skin peeling, hemolysis, chest pain, syncope, angina, arrhythmias, cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, thrombocytopenia, intrahepatic cholestatic jaundice, acute respiratory distress syndrome (ARDS), renal failure, renal dysfunction, interstitial nephritis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), acute muscular

Mild side effects

Abdominal pain, swelling/edema, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial swelling, fever, orthostatic hypotension, syncope, angina, arrhythmia (a-fib, bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, loss of appetite, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis, vomiting

This medication is sensitive to light and should be stored in a light-protective container. Additionally, to prevent damage to the medication, it is important to store it at room temperature, specifically between 1 degree and 30 degrees Celsius.

Appearance

Light yellow oval film-coated tablets

Package unit

30 tablets/bottle