Gastric Capsule 37.5 mg (Roxatidine Acetate Hydrochloride)

Adult dose

Adults: 1) Gastric and duodenal ulcers, reflux esophagitis, Zollinger-Ellison syndrome: Administer 75mg of roxatidine acetate hydrochloride orally twice daily after breakfast and dinner. For gastric and duodenal ulcers, 150mg may also be administered once daily in the evening. Gastric and duodenal ulcers are usually treated within 4 weeks, but symptoms resolve within a few days. If an ulcer has not healed after 4 weeks of treatment, continue the same dose for an additional 2 weeks. In patients with impaired renal function and creatinine clearance of approximately 20‐50mL/min, administer 75mg once daily in the evening. If creatinine clearance is 20mL/min or less, administer 75mg every 2 days in the evening. 2) Acute gastritis and acute exacerbation of chronic gastritis: Administer 75mg once daily after the evening meal or at bedtime. 3) Preanesthetic administration: Administer 75mg twice (at bedtime on the day before surgery and 2 hours before induction of anesthesia on the day of surgery). Adjust the dose appropriately according to age and symptoms.

This medication should not be used in patients allergic to this medication or any of its components. Patients with liver dysfunction or impaired kidney function should use this medication with caution. In particular, in cases of weak kidney function, the dose should be reduced, or the dosing interval should be extended. Elderly patients may also have decreased kidney function, so careful administration is necessary. Patients with past drug allergic reactions should use this medication cautiously. During the use of this medication, severe allergic reactions such as shock may occur, so symptoms should be closely monitored, and if any abnormalities arise, the medication should be discontinued immediately, and medical attention should be sought. Allergic symptoms such as rash or itching may occur rarely, so if these symptoms occur, medication should be stopped. Blood tests may reveal a decrease in platelet count, anemia, or reduction in immune cells, necessitating regular blood tests, and if any abnormalities are found, medication should be discontinued. Liver function abnormalities may occur, so periodic liver function tests are necessary, and if liver enzyme levels increase or jaundice symptoms appear, medication should be stopped immediately. Gastrointestinal symptoms such as constipation, diarrhea, nausea, abdominal distension, and dry mouth may occur, so caution is advised. Neurological symptoms such as confusion, hallucinations, drowsiness, insomnia, dizziness, and headache may rarely occur. Serious skin reactions may occur, so if there are skin rashes or mucosal abnormalities, medication should be stopped immediately. If there is a sudden increase in muscle pain or muscle-related test results, medication should be stopped immediately, and medical attention should be sought. Gynecomastia, excessive milk secretion, fatigue, and hypertension are also rare side effects that may occur. There may be interactions when used with other medications, so consult a doctor or pharmacist. Women who are pregnant or may become pregnant should carefully consider the benefits and risks of using this medication. Nursing mothers are advised to avoid breastfeeding during treatment, as this medication may be passed into breast milk. This medication is not used in children under 14 years of age, as safety has not been established. This medication is primarily excreted through the kidneys, so dosage adjustments may be necessary for the elderly based on kidney function. This medication must be kept out of reach of children, and care should be taken not to transfer it to another container as it may change the quality or lead to accidents.

shock

This medication should be stored in a sealed container that is not exposed to air or humidity, and it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the effectiveness of the medication and ensure safe use.

Appearance

Hard capsule with a light green upper part and a white lower part, containing white granules

Package unit

30 capsules/bottle, 250 capsules/bottle