Dexiwon Soft Capsule (Dexibuprofen)

Adult dosage

Administer 300 mg of dexibuprofen orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen daily.

This medication can cause gastrointestinal bleeding in people who regularly consume more than 3 drinks per day, so consultation with a doctor or pharmacist is essential. This drug may increase the risk of cardiovascular disease; individuals with a history of cardiovascular disease or risk factors should take it with caution, and seek medical advice immediately if cardiovascular symptoms occur. There are risks of gastrointestinal bleeding, ulcers, perforations, etc., so those with a history of gastrointestinal disease or the elderly should be particularly cautious and should stop taking the drug and consult a doctor if gastrointestinal symptoms appear. Patients with gastrointestinal ulcers or bleeding, severe liver, kidney, or heart disease, or those with an allergic reaction to aspirin or other nonsteroidal anti-inflammatory drugs should not take this medicine. The risk of gastrointestinal bleeding may increase when used concurrently with aspirin or other nonsteroidal anti-inflammatory drugs, so do not take them together, or with certain medications like methotrexate. During treatment with this drug, it is recommended to stop breastfeeding or discontinue the medication, as dizziness or fatigue may occur, requiring caution when driving or operating machinery. Individuals with blood disorders, liver or kidney function abnormalities, high blood pressure, heart failure, or allergic history must consult healthcare professionals before use. If severe allergic reactions, skin rashes, gastrointestinal bleeding symptoms, breathlessness, liver dysfunction, kidney function decline, or cardiovascular symptoms occur while taking this medication, stop immediately and consult a doctor. Regular blood tests and liver and kidney function tests are required with long-term use, and it is advisable to use the minimum effective dose for the shortest duration possible. During pregnancy, especially after 6 months, it should be avoided as it may adversely affect the fetus, and women planning pregnancy should consult a healthcare professional before use. In case of overdose, immediately visit a medical institution for appropriate treatment and keep out of reach of children, avoiding direct sunlight and storing in a cool, dry place.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanying cough and fever, yellowing of skin or eyes (jaundice), profound fatigue, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• upper abdominal pain
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

Do not take this medication with aspirin or other nonsteroidal anti-inflammatory drugs. Avoid concomitant use with high-dose (15 mg/week or more) methotrexate. Also avoid glucocorticoids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors, angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants (such as warfarin), baclofen, and immunosuppressants.

This medication may be sensitive to air or moisture, and should be stored in a tightly closed container. It is best to maintain a storage temperature between 1°C to 30°C.

Appearance

A light teal transparent oval soft capsule containing a colorless transparent liquid.

Package unit

10 capsules/PTP/case