Medication info

Lozakom Tablets

Prescription medicationApproval withdrawn
Ingredient · strength
Losartan Potassium›Strength being verifiedHydrochlorothiazide›Strength being verified
Manufacturer / importer
한림제약(주)
Appearance
Yellow oval film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 200808459 · Notified 2008.08.06

This product's status changed to Approval withdrawn on 2023.07.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement of blood pressure control in hypertension
Who uses it
Adults · Children
Adult dosage
Adults should take Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg as a standard dose, once daily. A dose exceeding Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg per day is not desirable. If blood pressure control is needed, the following adjustments and titrations are possible. 1) Start with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily, and;
Children's dosage
There is no experience of use in children and adolescents (under 18 years), so the combination of Losartan and Hydrochlorothiazide should not be administered.

Ingredients

Manufacturer
한림제약(주)

Efficacy & effects

Improvement of blood pressure control in hypertension

  • Hypertension
View approved original text

This medication, which combines Losartan Potassium and Hydrochlorothiazide, helps to lower blood pressure more effectively in patients with hypertension for whom blood pressure control is difficult with monotherapy. This contributes to the prevention of complications such as heart disease and stroke, and is therefore used to manage hypertension and maintain health.

Dosage and Administration

Adult dosage

Adults should take Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg as a standard dose, once daily. A dose exceeding Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg per day is not desirable. If blood pressure control is needed, the following adjustments and titrations are possible. 1) Start with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily, and;

Children's dosage

There is no experience of use in children and adolescents (under 18 years), so the combination of Losartan and Hydrochlorothiazide should not be administered.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with an allergy to this medication or its components, those with very poor kidney function, pregnant women, and patients with certain electrolyte imbalances should not take this medication. Patients with very low blood pressure, kidney or liver problems, or a history of diabetes or gout should take this medication with caution and consult a physician if necessary. During treatment with this medication, symptoms such as dizziness, drowsiness, and low blood pressure may occur, so care should be taken when driving or operating machinery. Regular blood tests should be done during treatment to monitor electrolyte status and kidney function, and care should be taken to ensure potassium levels do not become too high or too low. There may be interactions with other medications, so if this medication is taken with potassium-sparing diuretics, potassium supplements, certain analgesics, or antidiabetic medications, it is essential to consult a doctor or pharmacist. This medication can react sensitively to sunlight, increasing the risk of skin cancer, so UV protection and skin monitoring are necessary during treatment. Breastfeeding women should discontinue breastfeeding or consult a physician when taking this medication because it may affect the baby. It is a principle not to administer this medication to children and adolescents, as safety has not been established. In the case of overdose, hypotension and cardiac rhythm abnormalities may occur, so the dosage should be strictly followed, and if any abnormal symptoms appear, immediate consultation with medical personnel is required. When storing this medication, keep it out of reach of children and store it sealed in its original container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress combined with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headaches, lightning headaches, seizures, confusional state, visual disturbances, paralysis, urination changes

Mild side effects

  • Abdominal pain
  • swelling
  • palpitations
  • lower back pain
  • dizziness
  • cough
  • sinusitis
  • upper respiratory infection
  • weakness/fatigue
  • diarrhea
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  • nausea
  • headache
  • bronchitis
  • pharyngitis
  • chest pain
  • facial swelling
  • fever
  • orthostatic hypotension
  • fainting
  • angina
  • arrhythmia
  • hypotension
  • loss of appetite
  • constipation
  • toothache
  • dry mouth
  • indigestion
  • flatulence
  • gastritis
  • vomiting
  • malaise
  • anemia
  • gout
  • arm pain
  • joint pain
  • arthritis
  • fibromyalgia
  • hip pain
  • joint swelling
  • knee pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that blocks light, at a temperature between 1 degree and 30 degrees Celsius. Storing it this way helps to maintain the medication's effectiveness and prevents deterioration.

Appearance and packaging

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.