Medication info
Asquare Tablet

Asquare Tablet

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium Hydrate›10.85mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200808377 · Approved 2008.08.05 · Insurance code 671702270

Summary

Main use
(Hypertension, Angina) Reduction of cardiovascular risk and improvement of dyslipidemia
Who takes it
Adults
Adult dose
As Amlodipine (Es Amlodipine), take 5 (2.5) mg orally once daily, and the dose may be increased up to the maximum of 10 (5) mg daily depending on the patient's response. Atorvastatin starts at 10 mg once daily and may be increased to 20 mg or 40 mg as needed. The dosage may be adjusted in the range of 10 mg to 80 mg once daily, irrespective of meals.

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

(Hypertension, Angina) Reduction of cardiovascular risk and improvement of dyslipidemia

  • Hypertension
  • fixed coronary obstruction
  • vascular spasm of coronary arteries
  • vasoconstriction
  • myocardial ischemia
  • angina
  • heart failure
  • decreased cardiac output
  • myocardial infarction
  • stroke
  • chronic stable angina
  • retinopathy
View approved original text

This medicine is used for patients who need to take both Amlodipine and Atorvastatin simultaneously. Amlodipine helps to treat cardiovascular conditions such as hypertension, stable angina, and variant angina due to vascular spasms. It also reduces the risk of hospitalization due to angina in patients with coronary heart disease and the risk related to vascular interventions. Atorvastatin reduces the risk of cardiovascular diseases such as myocardial infarction, stroke, and angina, and is effective in improving hyperlipidemia and dyslipidemia. In particular, it lowers the incidence of cardiovascular events in diabetic patients or adult patients with cardiovascular risk factors. By using both drugs together, it effectively improves cardiovascular health by managing blood pressure and blood lipid levels.

How to take

Adult dose

As Amlodipine (Es Amlodipine), take 5 (2.5) mg orally once daily, and the dose may be increased up to the maximum of 10 (5) mg daily depending on the patient's response. Atorvastatin starts at 10 mg once daily and may be increased to 20 mg or 40 mg as needed. The dosage may be adjusted in the range of 10 mg to 80 mg once daily, irrespective of meals.

Precautions

This medicine should not be used in certain patients. For example, patients with allergies to this medicine or similar medications, those with severely impaired liver function, pregnant or breastfeeding women, patients with muscular diseases, patients with severely narrowed heart valves, and those within one month after a myocardial infarction should not take this medicine. There are also patients who need to exercise caution when using this medicine. Patients with severely impaired kidney function, the elderly, alcoholics, those with a history of liver disease, patients at high risk of muscle damage, heart failure patients, and those in hypertensive crises should use this medicine carefully. This medicine is primarily used to lower blood pressure and regulate blood lipids, and is generally well tolerated. However, symptoms such as mild fatigue, edema, dizziness, headache, and nausea may occur. Rarely, muscle pain, impaired liver function, and allergic reactions may occur, so any abnormal symptoms should be discussed with a doctor immediately. This medicine is metabolized in the liver, so patients with poor liver function should have regular liver function tests, and treatment should be discontinued if symptoms of hepatitis or jaundice occur. Pregnant women or those who may become pregnant should not take this medicine, and if pregnancy is confirmed while on this medication, it should be stopped immediately. Additionally, breastfeeding women are advised not to take this medicine. This medicine may interact with other medications, especially those that are metabolized in the liver or can affect muscle; therefore, it is important to consult a doctor or pharmacist when taking these medications together. In cases of overdose, there is a risk of severe hypotension, arrhythmias, and shock, requiring immediate medical attention, and hemodialysis may not be effective. The safety of this medicine has not been sufficiently established in children or the elderly, so special caution is necessary in these age groups. Finally, this medicine should be kept out of reach of children and should not be transferred to other containers for safety reasons.

Side effects and when to seek care immediately

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, oral/eye mucosal pain, shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever and breathing abnormalities, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • malaise
  • pain
  • weight increase/decrease
  • hypotension
  • vasculitis
  • muscle tension
  • sensory loss/paresthesia
  • peripheral neuropathy
  • syncope
  • altered taste
  • tremors
  • extrapyramidal symptoms
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • indigestion
  • gingival hyperplasia
  • gum proliferation
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps.

Not everyone experiences these, and they can vary from person to person.

Storage

This medicine should be stored in a tightly closed container to prevent air and moisture from entering, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medicine and prevents deterioration.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.