Barodipine Tablet 5mg (Amlodipine Besilate)

Adult dose

Adults should take 5mg of amlodipine orally once daily, which may be increased to a maximum of 10mg per day depending on the patient's response. Adjustments should be made according to age and symptoms.

This drug should not be administered to certain patients. For example, it is contraindicated in individuals with allergies to this drug or similar drugs, breastfeeding women, patients with severe liver dysfunction, those with severe aortic stenosis, and patients in shock. Additionally, caution is needed in patients with severe hypotension, those requiring dialysis for renal failure, elderly patients, and pregnant or potentially pregnant women. Generally, this drug is well-tolerated, but some patients may experience side effects such as flushing, fatigue, edema, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, various adverse reactions such as hypotension, vascular inflammation, neurological issues, digestive problems, and skin rashes have been reported. Patients with heart failure or liver dysfunction should be particularly careful when administering this drug, and blood pressure may gradually decrease even after discontinuation of the medication, requiring caution when combined with other antihypertensives. This drug may cause excessive hypotensive effects when taken with grapefruit or grapefruit juice, so it is advisable to avoid co-administration. Additionally, since interactions with certain medications may occur, it is important to consult a doctor or pharmacist if taking other medications. It is recommended that this drug not be used in pregnant women, except in special cases where safety has not been established, and breastfeeding should be discontinued if this drug is taken during lactation. Use is only recommended for children aged 6 years and older; its efficacy and safety in younger children have not been established. In case of overdose, risks such as hypotension, tachycardia, and shock are present, and immediate medical attention should be sought. This drug is not removed by hemodialysis, so prompt medical action is necessary if an overdose occurs. Finally, this drug is unlikely to significantly impair the ability to drive or operate machinery, but caution is necessary if dizziness or drowsiness occurs during use.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• hepatitis
• severe edema
• difficulty breathing
• respiratory distress

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This drug should be stored in a tightly sealed container to avoid exposure to air or moisture and should be kept at a temperature between 1 and 30 degrees Celsius. Storing this way will help maintain the effectiveness of the medication for a longer period.

Appearance

White octagonal tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)], 30 tablets/bottle, 300 tablets/bottle