Donepezil Tablets 10mg (Donepezil Hydrochloride Hydrate)

Adult dose

Adults: Take 5 mg of donepezil hydrochloride once daily before going to bed. If unusual dreams, nightmares, or sleep disturbances occur, consider taking it in the morning. The concentration of donepezil reaches a normal state 15 days after administration, so for 4-6 weeks, a dose of 5 mg should be administered. After this period, clinical responses should be evaluated to increase the dose to 10 mg; when administering 10 mg daily, attention should be paid to gastrointestinal adverse effects.

Child dose

Children: There is no experience of use in pediatrics.

This medication should not be used by individuals with allergies to specific ingredients. Especially those who have had hypersensitivity reactions to the components of this drug or to donepezil hydrochloride, piperidine derivatives should not take it. It is also safer for pregnant or possibly pregnant women, as well as nursing mothers, to avoid this medication. This medication contains lactose, so it should not be administered to patients with lactose intolerance or certain genetic issues. Caution is needed for those with heart disease or heart rhythm disorders when using this medication, as it can slow the heart rate or cause arrhythmias. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should use this medication cautiously, as it may increase gastric acid secretion and enhance gastrointestinal motility, worsening symptoms. Patients with asthma or obstructive pulmonary disease should also be cautious, as symptoms may worsen when taking this medication. Those with extrapyramidal disorders such as Parkinson's disease should definitely consult before using this medication, as it may exacerbate symptoms. Individuals allergic to the dye included in this medication should also take precautions. Serious side effects such as fainting, heart problems, gastrointestinal bleeding, liver function abnormalities, seizures, and movement disorders may occur during use, so any unusual symptoms should be reported to a doctor immediately. This medication is used for the treatment of memory disorders but is not effective for other types of dementia or cognitive decline, and treatment should be supervised by a specialist. For those with heart disease or electrolyte imbalances, regular electrocardiograms may be necessary due to an increased risk of heart-related side effects. Caution is required when driving or operating machinery as dizziness or fatigue may occur. Interactions with other medications are possible, so it is essential to inform about any current medications, especially heart-related drugs, antibiotics, and antidepressants, as caution is needed when combined. Women who are pregnant or breastfeeding should avoid this medication unless necessary and should discuss with experts regarding stopping breastfeeding if it must be taken. Safety has not been established for children, so it is not used in pediatric cases. In cases of overdose, symptoms such as nausea, vomiting, heart problems, and difficulty breathing may appear, so the dosage must be strictly adhered to; in case of overdose, immediate contact with a medical institution is necessary. This medication should be stored out of reach of children and it is important not to transfer it to other containers to maintain product quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain of the oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• fever
• drowsiness
• dizziness
• insomnia

This medication should be stored in a tightly sealed container to prevent the entry of air and moisture, and it is best kept at room temperature between 1 and 30 degrees Celsius. This storage method helps maintain the medication's effectiveness for a longer time.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle