Tumix Tablets 5/10 mg (Amlodipine, Atorvastatin)

Adult dose

For amlodipine (as esamlodipine), 5 (2.5) mg should be administered orally once daily, and the dose may be increased up to 10 (5) mg daily depending on the patient's response. Atorvastatin should start at 10 mg once daily, and may be increased to 20 mg or 40 mg once daily if necessary. The usual dosing range is from 10 mg to 80 mg once daily. After initiating treatment and adjusting the dosage, lipid levels should be analyzed after 2 to 4 weeks.

This medication should not be administered to certain patients. For example, patients who have had an allergic or hypersensitive reaction to this medication or similar drugs, patients with severely impaired liver function, patients with active liver disease or those with persistently elevated liver enzyme levels, patients with obstructed bile secretion or muscle diseases, pregnant women or those who may become pregnant, nursing women, patients with severe aortic stenosis, patients in shock, patients with severely low blood pressure, patients who have recently had a myocardial infarction, patients with unstable angina, and patients taking specific antiviral medications. Additionally, patients with severely impaired kidney function, elderly patients, those with a history of alcohol abuse or liver disease, and patients at risk for muscle disorders need special caution when taking this medication. Blood tests may be recommended to check for muscle damage before taking this medication. This medication is generally well tolerated; however, mild to moderate side effects may occur, such as flushing, fatigue, edema, palpitations, dizziness, headache, nausea, abdominal pain, weakness, lethargy, pain, weight gain/loss, low blood pressure, vasculitis, muscle tightness, sensory decrease/alteration, peripheral neuropathy, syncope, altered taste, tremors, extrapyramidal symptoms, erectile dysfunction, gynecomastia, changes in bowel habits, dry mouth, indigestion, gingival hypertrophy, gingival hyperplasia, pancreatitis, vomiting, hyperglycemia, joint pain, lower back pain, muscle cramps. Severe side effects reported include urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blistering, skin sloughing, mouth/eye mucosal pain, toxic epidermal necrolysis, shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe malaise, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blistering, skin sloughing, mouth/eye mucosal pain, toxic epidermal necrolysis, shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe malaise, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication must be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 15 and 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle