Medication info
Megesia Tablets 160mg (Megestrol Acetate)

Megesia Tablets 160mg (Megestrol Acetate)

Prescription medicationTabletOral
Ingredient · strength
Megestrol Acetate›160mg / 1 tablet
Manufacturer / importer
(Ltd.) Darim Biotech
Appearance
White oval-shaped tablet
Packaging
Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle, PTP - 100 tablets/PTP [10 tablets/PTP x 10]
Approval status
Active

MFDS item code 200807474 · Notified 2008.07.07 · Insurance code 664601230

Summary

Main use
Treatment of cancer- and AIDS-related symptoms (such as loss of appetite); palliation of advanced breast cancer and endometrial cancer
Who takes it
Adults
Adult dose
1. Breast cancer : Administer megestrol acetate orally at a dose of 160mg per day in divided doses. 2. Endometrial cancer : Administer this drug orally at a dose of 40~320mg per day in divided doses. 3. Treatment of anorexia, cachexia, or significant unexplained weight loss in patients with cancer or AIDS : Administer megestrol acetate orally at a dose of up to 800mg once daily. In clinical trials, clinical benefit was demonstrated with megestrol acetate doses of 400~800 mg per day. Treatment should be continued for at least 2 months, an appropriate period for assessing the effect of this drug.

Ingredients

Manufacturer
(Ltd.) Darim Biotech

Efficacy & effects

Treatment of cancer- and AIDS-related symptoms (such as loss of appetite); palliation of advanced breast cancer and endometrial cancer

  • Recurrent breast cancer
  • metastatic breast cancer
  • inoperable breast cancer
  • endometrial cancer
  • anorexia
  • cachexia
  • significant weight loss
View approved original text

This medication is used to relieve symptoms in patients with recurrent, metastatic, and inoperable breast cancer and endometrial cancer. However, it is not suitable as a substitute for surgical or radiation therapy. Additionally, it is effective in treating patients with anorexia, cachexia, or unexplained significant weight loss due to cancer or AIDS. This efficacy helps to improve the quality of life of patients.

How to take

Adult dose

1. Breast cancer : Administer megestrol acetate orally at a dose of 160mg per day in divided doses. 2. Endometrial cancer : Administer this drug orally at a dose of 40~320mg per day in divided doses. 3. Treatment of anorexia, cachexia, or significant unexplained weight loss in patients with cancer or AIDS : Administer megestrol acetate orally at a dose of up to 800mg once daily. In clinical trials, clinical benefit was demonstrated with megestrol acetate doses of 400~800 mg per day. Treatment should be continued for at least 2 months, an appropriate period for assessing the effect of this drug.

Precautions

This medication may cause serious risks to the fetus if taken during pregnancy, so it should not be used by women who are pregnant or may become pregnant. In particular, taking this medication or similar progestins during the first four months of pregnancy can lead to fatal harm to the fetus, and it should absolutely not be used. This medication should also not be used for the prevention or treatment of habitual or threatened miscarriage. Furthermore, long-term use of this medication may increase the risk of developing diabetes or worsening existing diabetes, and there is also a risk of adrenal insufficiency. If symptoms of adrenal insufficiency appear, such as dizziness, nausea, vomiting, weakness, etc., immediate consultation with healthcare professionals is necessary. Patients allergic to this medication or with specific genetic issues such as lactose intolerance should not take it. Special caution is required for patients with a history of thromboembolism or diabetes, as it may affect thrombosis or blood sugar control. Various side effects such as breast cancer, endometrial cancer, thrombosis, hypertension, hair loss, rash, weakness, etc., may occur during the use of this medication, and any unusual symptoms should be discussed with a physician. Women who are pregnant or breastfeeding should not use this medication and should stop breastfeeding during treatment. Safety in pediatrics has not been established, so it should not be used in children. No particular harmful symptoms have been reported in cases of overdose, but dialysis is ineffective, so in the event of an overdose, immediate visit to a medical institution is necessary. This medication should be kept out of the reach of children, and it is safer not to transfer it to another container. During the use of this medication, the cause of weight loss should be accurately identified and treated, and caution is needed as the risk of respiratory infections may increase with long-term use.

Side effects

  • Thrombophlebitis
  • thromboembolic symptoms
  • pulmonary embolism
  • glucose intolerance
  • heart failure
  • nausea
  • vomiting
  • edema
  • sudden uterine bleeding
  • dyspnea
Show 78 more
  • tumor erythema
  • hyperglycemia
  • alopecia
  • hypertension
  • carpal tunnel syndrome
  • emotional changes
  • flushing
  • fatigue
  • weakness
  • drowsiness
  • sweating
  • rash
  • gynecomastia
  • hearing loss
  • pain
  • Cushingoid facies
  • diarrhea
  • diarrhea
  • erectile dysfunction
  • rash
  • abdominal distension
  • hypertension
  • weakness
  • insomnia
  • nausea
  • anemia
  • fever
  • decreased libido
  • dyspepsia
  • hyperglycemia
  • headache
  • pain
  • vomiting
  • pneumonia
  • frequent urination
  • amblyopia
  • constipation
  • dry mouth
  • hepatomegaly
  • increased salivation
  • oral candidiasis
  • cardiomyopathy
  • palpitations
  • dyspnea
  • cough
  • pharyngitis
  • pulmonary dysfunction
  • leukopenia
  • proteinuria
  • urinary incontinence
  • urinary tract infection
  • gynecomastia
  • paresthesia
  • confusion
  • seizures
  • depression
  • neuropathy
  • sensory loss
  • abnormal thoughts
  • alopecia
  • herpes
  • itching
  • bullous rash
  • sweating
  • skin disorders
  • elevated LDH
  • edema
  • peripheral edema
  • chest pain
  • abdominal pain
  • infection
  • candidiasis
  • sarcoma
  • spontaneous bleeding
  • anxiety
  • stomatitis
  • mucositis
  • shoulder pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 15 to 25 degrees Celsius at room temperature to preserve the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

White oval-shaped tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle, PTP - 100 tablets/PTP [10 tablets/PTP x 10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.