Duo-Sartan Tablet 160/12.5 mg

Adult dose

The recommended adult dose is 80 mg valsartan/12.5 mg hydrochlorothiazide once daily, taken with a small amount of water regardless of meals. A dose of 160 mg valsartan/12.5 mg hydrochlorothiazide is applied when prescribed for blood pressure reduction. For patients with renal impairment, no dose adjustment is necessary for mild to moderate renal impairment (creatinine clearance of 30 mL/min or more). For patients with liver impairment

This medication can cause serious harm to the fetus, especially during the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. It should not be used in patients who are allergic to any of the ingredients or have certain liver or kidney diseases. Patients with low blood pressure, electrolyte imbalances, or issues with kidney or liver function should use this medication with caution. This medication lowers blood pressure and may cause dizziness or drowsiness when starting treatment, so caution is advised while driving or operating machinery. It can affect potassium levels, so potassium supplements should not be taken without consulting a doctor, and regular blood electrolyte tests should be performed. This medication may increase skin sensitivity to sunlight, so sun exposure should be avoided, and any unusual skin changes should be reported to a doctor immediately. There may be interactions with other medications, especially when used with lithium, NSAIDs, and potassium-sparing diuretics, so a doctor's instructions must be strictly followed. Women who are pregnant, planning to become pregnant, or nursing should avoid using this medication. Safety in children has not been established, so it is not to be used in pediatric patients. In case of overdose, serious side effects such as low blood pressure and electrolyte abnormalities may occur, requiring immediate contact with a medical facility. This medication should be stored in a cool, dry place away from moisture and direct sunlight, and out of reach of children.

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, anaphylactic-like symptoms, angioedema, hepatitis, renal failure, hyperkalemia, hyponatremia, shock, fainting, loss of consciousness, necrotizing vasculitis, toxic epidermal necrolysis (Lyell's syndrome), interstitial pneumonia, pulmonary edema, exacerbation of systemic lupus erythematosus, hypoglycemia, rhabdomyolysis, angioedema, serum sickness and vasculitis among other hypersensitivity reactions, acute respiratory distress syndrome (ARDS)

Mild side effects

• Headache
• dizziness
• rhinitis
• fatigue
• back pain
• cough
• upper respiratory infection
• diarrhea
• joint pain
• abdominal pain

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It should also be kept in a cool place at or below 30 degrees Celsius to maintain its efficacy.

Appearance

Dark red oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle