Medication info
Coibes Dil Tablets 300/12.5 mg

Coibes Dil Tablets 300/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Irbesartan›300mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
안국약품(주)
Appearance
Pink, bilaterally convex, oval film-coated tablets
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 200807418 · Notified 2008.07.04 · Insurance code 650203000

Summary

Main use
Blood pressure control and therapeutic effect for essential hypertension
Who takes it
Adults · Children
Adult dose
This medication is administered once daily, regardless of meals. 1. For adult patients whose blood pressure is not effectively controlled with monotherapy: - Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg take 1 tablet once daily. - Irbesartan 300 mg/Hydrochlorothiazide 12.5 mg take 1 tablet once daily. - Irbesartan 300 mg/Hydrochlorothiazide 25 mg take 1 tablet once daily. -
Child dose
The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age.

Ingredients

Manufacturer
안국약품(주)

Efficacy & effects

Blood pressure control and therapeutic effect for essential hypertension

  • Essential hypertension
  • moderate hypertension
  • severe hypertension
View approved original text

This medication is used to control blood pressure in patients with essential hypertension. It is effective even when blood pressure is insufficiently controlled with monotherapy. Additionally, it is used as an initial therapy in patients with moderate or severe hypertension who require combination therapy to achieve target blood pressure. Therefore, this medication helps in managing blood pressure for hypertensive patients.

How to take

Adult dose

This medication is administered once daily, regardless of meals. 1. For adult patients whose blood pressure is not effectively controlled with monotherapy: - Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg take 1 tablet once daily. - Irbesartan 300 mg/Hydrochlorothiazide 12.5 mg take 1 tablet once daily. - Irbesartan 300 mg/Hydrochlorothiazide 25 mg take 1 tablet once daily. -

Child dose

The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy; therefore, it should be discontinued immediately if pregnancy is confirmed. Women who are pregnant or may become pregnant, breastfeeding mothers, and patients who are allergic to this medication or its components should not take it. Patients with severely compromised kidney function or anuria should also avoid this medication. Patients with hypotension, kidney disease, liver disease, heart valve disease, glaucoma, or a history of skin cancer should use this medication with caution. The hydrochlorothiazide component may cause sensitivity to sunlight, so it is important to minimize UV exposure and regularly check skin condition while taking this medication. Side effects such as dizziness, fatigue, nausea, vomiting, abnormal urination may occur; if symptoms are severe, consult a physician. Regular blood tests to check kidney function and electrolyte levels are necessary, especially monitoring potassium level fluctuations. If experiencing symptoms of hypoglycemia or receiving treatment for diabetes, consulting a professional before taking this medication is necessary. Interactions can occur when taken with other antihypertensives, lithium, potassium supplements, non-steroidal anti-inflammatory drugs, so it is crucial to inform healthcare professionals. Safety and efficacy in children and adolescents have not been established; therefore, it is not recommended for them. Elderly patients may have increased sensitivity to this medication, so more caution is needed. In the case of overdose, serious symptoms like hypotension, electrolyte imbalance, dehydration may occur; adherence to the prescribed dosage is critical, and if any unusual symptoms arise, immediate consultation with healthcare professionals is needed. This medication should be kept out of reach of children and stored in its original container to prevent misuse or degradation of quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in the oral/ocular mucosa, severe dermatological reactions, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities (jaundice), sudden

Mild side effects

Dizziness, fatigue, nausea/vomiting, abnormal urination, increased BUN, elevated creatine kinase, increased creatinine, headache, syncope, hypotension, tachycardia, flushing, cough, diarrhea, indigestion, altered taste, hepatitis, abnormal liver function, sexual dysfunction, changes in libido, kidney function impairment in patients at risk, limb swelling, arthralgia, myalgia, tinnitus, thrombocytopenia, hypoglycemia, depression, sleep disturbances, orthostatic hypotension

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to protect it from air and moisture, and it is recommended to store it at room temperature between 1 to 30 degrees Celsius. Doing so helps maintain the effectiveness of the medication and prevents deterioration.

Appearance and packaging

Appearance

Pink, bilaterally convex, oval film-coated tablets

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.