Valsartan and Hydrochlorothiazide Tablets

Adult dose

Take 1 tablet of valsartan 80 mg/hydrochlorothiazide 12.5 mg once daily with a small amount of water, regardless of meals. If prescribed valsartan 160 mg/hydrochlorothiazide 12.5 mg for blood pressure lowering, take the prescribed dose. No dosage adjustment is required for patients with mild to moderate renal impairment (creatinine clearance > 30 mL/min).

This medication may cause serious harm or death to the fetus if taken during pregnancy, particularly in the second and third trimesters; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients who have had an allergic reaction to this medication or its components, those who are pregnant or may become pregnant, and those with severe liver or kidney disease should not use this medication. This medication should be used with caution in patients with certain conditions such as electrolyte imbalance, liver or kidney dysfunction, cardiovascular disease, diabetes, and the elderly, as it can cause significant drops in blood pressure leading to dizziness or fainting. During treatment, potassium levels and kidney function should be monitored regularly, and excessive intake of potassium supplements or potassium-rich foods without consulting a physician should be avoided. This medication can interact with various drugs, so patients taking other medications must inform their healthcare provider, especially when used concurrently with lithium, non-steroidal anti-inflammatory drugs (NSAIDs), or potassium-sparing diuretics. Patients should inform their healthcare provider immediately if new skin lesions appear or existing skin conditions worsen while taking this medication and should avoid sun or ultraviolet exposure while taking appropriate skin protective measures. Dizziness or drowsiness may occur when driving or operating machinery, so caution is advised, especially during initial dosing when symptomatic hypotension may arise. Overdose may result in hypotension, arrhythmias, electrolyte disturbances, and requires immediate medical attention. The safety and efficacy of this medication have not been established in children, so it is generally not recommended for pediatric use. Store this medication out of the reach of children, avoiding moisture, and keeping it in the original container.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, angioedema, hepatitis, renal failure, hyperkalemia, hyponatremia, shock, fainting, loss of consciousness, aplastic anemia, hemolytic anemia, necrotizing vasculitis, toxic epidermal necrolysis (Lyell's syndrome), interstitial pneumonia, pulmonary edema, exacerbation of systemic lupus erythematosus, hypoglycemia, rhabdomyolysis, angioedema, acute respiratory distress syndrome (ARDS), angioedema, acute

Mild side effects

• Headache
• dizziness
• nasopharyngitis
• fatigue
• back pain
• cough
• upper respiratory tract infection
• diarrhea
• arthralgia
• abdominal pain

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and kept in a cool place below 30 degrees Celsius to maintain its effectiveness.

Appearance

Bright orange oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle