Osnel Tablet 35 Milligrams (Sodium Risedronate Dihydrate)

Adult dose

1. Adults : Administer 35 mg of risedronate sodium orally once weekly. 2. Elderly patients : No dose adjustment is necessary in elderly patients (over 60 years) because the bioavailability and pharmacodynamics of this drug are similar to those in younger people. 4. Patients with renal impairment : No dose adjustment is necessary in patients with creatinine clearance of 30 mL/min or greater. This drug is contraindicated in patients with severe renal impairment with creatinine clearance below 30 mL/min. ○ Since food interferes with the absorption of this drug, for adequate absorption, take it at least 30 minutes before breakfast or at least 2 hours apart from food or beverages at any time of day. Take this drug with a sufficient amount of plain water (170 ∼ 230 mL) in an upright position to help it reach the stomach easily and reduce the possibility of esophageal irritation. Taking this drug with other beverages, including mineral water, may reduce its absorption. Do not chew or suck this drug because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. ○ If the patient forgets to take the dose on the scheduled day, take it the next morning when remembered. Resume the next dose on the originally scheduled day. Do not take 2 tablets on the same day.

Child dose

The safety and efficacy in children younger than 18 years have not been established.

This medication is used as an oral bisphosphonate to strengthen bones. However, it can irritate the mucosa of the stomach and esophagus, so caution is especially warranted for those with esophageal diseases or conditions such as gastritis, duodenitis, or ulcers. Take this medication with a full glass of water and remain upright for at least 30 minutes after taking it. Failure to do so may increase the risk of esophageal irritation or damage. This medication should not be administered to individuals with esophageal strictures, hypocalcemia, severe renal impairment, or those who are pregnant or breastfeeding. Also, individuals who are lactose intolerant should avoid preparations containing lactose. If symptoms such as dysphagia, chest pain, or heartburn occur while taking this medication, discontinue use immediately and consult a physician. It is important to ensure an adequate intake of calcium and vitamin D while taking this medication, and to take it with a time gap from any medications or foods containing calcium, magnesium, iron, etc., as they may interfere with the absorption of this medication. Rare side effects such as osteonecrosis of the jaw have been reported, so if dental treatment is needed during this period, consult the treating physician regarding the decision to discontinue the medication. Additionally, if long-term use of this medication leads to pain in the legs or pelvic region, one should suspect the possibility of atypical fractures and seek medical evaluation. This medication may cause various side effects, including gastrointestinal adverse reactions, musculoskeletal pain, skin rashes, and inflammation of the eyes, so notify healthcare professionals immediately if any unusual symptoms occur. Use of this medication is not recommended during pregnancy or breastfeeding, and consultation with a physician is advised if necessary. For safety, keep this medication out of reach of children and do not transfer it to another container.

• Esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• hemorrhage
• gastric ulcer
• duodenal ulcer
• dyspepsia
• diarrhea

Store this medication in a tightly sealed container to prevent exposure to air or moisture, and keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Light orange, rectangular film-coated tablet

Package unit

4 tablets/box[((4 tablets/PTP)x1)]