Actipio Tablet 30 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is initiated at 15 mg once daily, and may be increased to 30 mg once daily if the effect is insufficient. Maximum dosage should not exceed 30 mg once daily in monotherapy or in combination with sulfonylureas, metformin, or insulin. This drug is administered orally once daily regardless of meals.

Child dose

There is no experience with the use of this medication in children under 18 years of age; therefore, administration is not recommended.

This medication is used for the treatment of type 2 diabetes and works together with insulin to control blood sugar. However, this medication may impose a burden on the heart in some patients, so it should not be administered to patients with heart failure or a history of heart failure. During treatment with this medication, patients should be monitored closely for symptoms of heart failure such as weight changes, shortness of breath, and swelling, with immediate consultation with a physician if symptoms occur. Additionally, this medication may cause fluid retention leading to edema, so patients with existing edema or at high risk of cardiovascular disease should be especially cautious. Patients with active bladder cancer or a history of bladder cancer should not take this medication either. It is safest not to administer this medication to patients with severe liver or kidney impairment. Women who are pregnant or may become pregnant should avoid using this medication, and premenopausal women should use appropriate contraception as this medication may stimulate ovulation and increase the risk of pregnancy. This medication can increase the risk of hypoglycemia when used in combination with other diabetes medications, so patients should be well aware of hypoglycemia symptoms and dosage adjustments of other medications may be necessary. Regular monitoring of blood glucose and liver function tests should be performed during treatment, and any sudden weight gain, edema, urinary problems, or hematuria should be reported to a physician immediately. Elderly patients or those with weak kidney or liver function should be treated with greater caution, and this medication should be taken once a day regardless of meals, being careful not to double dose the next day if a dose is missed. In case of overdose, appropriate treatment should be administered based on symptoms and the medication should be stored out of the reach of children.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight changes, shortness of breath, edema), severe edema, hives, liver abnormalities (jaundice), liver failure, severe dermatological reactions (severe rash with fever, blistering, skin peeling, mucosal pain in mouth/eyes), severe allergic reactions, severe neurological symptoms (severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis), difficulty breathing, asthma

Mild side effects

• Headache
• upper respiratory tract infections
• sinusitis
• myalgia
• pharyngitis
• abdominal distension
• weight gain
• hypoglycemia
• urinary tract infections
• low back pain

This medication should be protected from light and moisture and should be stored between 15 and 30 degrees Celsius, preferably around 25 degrees. This way of storage can help maintain the medication's efficacy for a longer period.

Appearance

Flat round tablets that are white or gray

Package unit

30 tablets/bottle