AMBIZ Tablet (Amlodipine Besylate)

Adult dose

Adults: Administer 5 mg orally once daily as Amlodipine, which may be increased to a maximum of 10 mg daily based on the patient's response. Adjust according to age and symptoms.

This medication should not be used in certain patients. For example, it should not be administered to individuals who are allergic to this drug or similar types of medications, those with severe hepatic impairment, severe aortic stenosis, patients in a state of shock, and breastfeeding women. Additionally, caution is advised when prescribing to patients with severe hypotension, patients requiring dialysis due to renal failure, elderly patients, and women who are pregnant or may become pregnant. Common side effects include flushing, fatigue, edema, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, various side effects such as hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, dyspepsia, weight changes, and skin rashes have been reported. Patients with heart failure or impaired liver function should be more careful when using this medication, and its effects may appear gradually, making it unsuitable for acute heart conditions. This medication may interact with various other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. It is particularly advised to avoid grapefruit juice as it may enhance blood pressure lowering effects. In pregnant or breastfeeding women, the safety of this medication has not been established, so it should only be used when absolutely necessary, and breastfeeding should be discontinued if possible. This medication can be used in children over 6 years of age, but its effects and safety have not been established for children under 6. Overdose may lead to severe hypotension and cardiac function decline, requiring immediate emergency treatment. This medication is not removed by dialysis, so caution is necessary. Lastly, while this medication is unlikely to impair driving or machine operation ability, be cautious as dizziness or drowsiness may occur as side effects.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• yellowing of the skin or eyes (jaundice)
• extreme fatigue
• toxic epidermal necrolysis
• angioedema
• erythema multiforme.

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

Store this medication in a tightly sealed container to protect it from air and moisture. It is advisable to keep the storage temperature between 1 to 30 degrees Celsius.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle