NovaTin Tablets (Amlodipine Besilate)

Adult dose

Administer 5 mg orally once daily as amlodipine, with the maximum dose increased to 10 mg per day based on patient response. Adjust according to age and symptoms.

This medication should not be used in patients who are allergic to this drug or similar medications. Women who are breastfeeding should avoid using this medication. It should not be administered to patients with severely impaired liver function, severely narrowed aortic valves, or those in a state of shock. Patients with severe hypotension, patients requiring dialysis due to renal failure, elderly patients, pregnant women, or women who may become pregnant should use this medication with caution. This drug effectively lowers blood pressure and is generally well tolerated, but side effects such as flushing, fatigue, edema, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea may occur. Rarely, various adverse reactions like hypotension, vasculitis, neurological abnormalities, erectile dysfunction, gastrointestinal issues, elevated blood sugar, myalgia, hematological abnormalities, insomnia, and skin rashes have been reported. In heart failure patients, there may be an increase in pulmonary edema, requiring caution, and patients with liver dysfunction may need dosage adjustments due to prolonged drug half-life. The effects of this medication appear gradually, making it unsuitable for acute angina. It is known to have little effect on the ability to drive or operate machinery. This medication can interact with several other drugs, so caution is needed when taken with grapefruit juice, certain antibiotics, antihypertensives, immunosuppressants, etc. Women who are pregnant or breastfeeding are recommended to avoid this medication, with the use during pregnancy only considered when no safe alternatives are available. In children, efficacy is confirmed for those older than 6 years; safety and efficacy in children under 6 years are not known. Overdosage can lead to severe hypotension and shock, necessitating immediate medical attention to receive appropriate care. There is no evidence that this medication causes carcinogenicity or genetic abnormalities, making it safe for long-term use.

Serious side effects

• Hives
• severe swelling (edema)
• hepatitis
• jaundice
• toxic epidermal necrolysis
• difficulty breathing
• respiratory distress
• angioedema
• allergic reactions
• severe allergic reactions

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White octagonal tablets

Package unit

30 tablets/bottle, 300 tablets/bottle