Medication info

Zafros XL Tablets 10 Milligrams (Alfuzosin Hydrochloride)

Prescription medicationTabletOralApproval withdrawn
Ingredient · strength
Alfuzosin Hydrochloride›10mg / 1 tablet
Manufacturer / importer
Yuhan Corporation
Appearance
Round tablets that are white to light yellow in color
Packaging
30 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 200805945 · Approved 2008.05.28

This product's status changed to Approval withdrawn on 2024.07.15. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of symptoms of benign prostatic hyperplasia; catheter-assisted treatment of associated acute urinary retention
Who takes it
Adults
Adult dose
The recommended dose is 10mg once daily, taken immediately after the evening meal. Swallow the tablet whole; do not chew it. When used as adjunctive therapy to catheterization for acute urinary retention associated with benign prostatic hyperplasia, the recommended dose is 10mg once daily, taken after a meal beginning on the first day of catheterization. Take it for 2-3 days while the catheter is in place and for 1 day after catheter removal, for a total of 3-4 days.

Ingredients

Manufacturer
Yuhan Corporation

Efficacy & effects

Treatment of symptoms of benign prostatic hyperplasia; catheter-assisted treatment of associated acute urinary retention

  • Functional symptoms of benign prostatic hyperplasia
  • acute urinary retention
View approved original text

This medication is used to treat functional symptoms such as urinary difficulties caused by benign prostatic hyperplasia. It can also be used as an adjunct treatment during catheterization in cases of acute urinary retention to help alleviate symptoms. Therefore, it aids in improving various issues related to prostatic enlargement.

How to take

Adult dose

The recommended dose is 10mg once daily, taken immediately after the evening meal. Swallow the tablet whole; do not chew it. When used as adjunctive therapy to catheterization for acute urinary retention associated with benign prostatic hyperplasia, the recommended dose is 10mg once daily, taken after a meal beginning on the first day of catheterization. Take it for 2-3 days while the catheter is in place and for 1 day after catheter removal, for a total of 3-4 days.

Precautions

This medication contains alfuzosin, and it is important not to use it in certain patients. For example, individuals with an allergy to this medication, those with orthostatic hypotension, severe liver or kidney dysfunction, intestinal obstruction, and those taking other alpha-blockers should not take this medication. Also, patients undergoing treatment for hypertension or elderly individuals may experience symptoms such as dizziness or fatigue for several hours after the first dose, hence caution is needed. Patients with heart conditions or those with a prolonged QT interval should also use this medication with care. Side effects such as dizziness, headache, dyspepsia, constipation, fatigue, and skin rash may occur when taking this medication, and in rare cases, serious heart problems or blood abnormalities may arise. Particularly, if a patient taking this medication is to undergo cataract surgery, there may be issues with pupil dilation during the surgery, and this should be communicated to healthcare professionals before the procedure. This medication should be swallowed whole, as breaking or chewing it may lead to imbalanced effects and increase the risk of side effects. Caution should be exercised when taking this medication along with other alpha-blockers, certain antihypertensives, nitrate medications, and some antifungals, as the risk of hypotension may increase. The safety of this medication during pregnancy or breastfeeding has not been established, so it is advisable not to use it in these cases. While taking this medication, dizziness or weakness may occur, so special care should be taken when driving or operating machinery. In case of overdose, immediate hospitalization is necessary for appropriate treatment, as this medication is difficult to remove through dialysis. Lastly, keep this medication out of the reach of children, and do not transfer it to other containers.

Side effects

  • fainting
  • dizziness
  • headache
  • vertigo
  • syncope
  • tachycardia
  • angina
  • intraoperative floppy iris syndrome
  • upper respiratory tract infections
  • bronchitis
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  • sinusitis
  • pharyngitis
  • rhinitis
  • nausea
  • abdominal pain
  • dyspepsia
  • constipation
  • diarrhea
  • hepatocellular liver damage
  • cholestatic liver disease
  • skin rash
  • pruritus
  • urticaria
  • angioedema
  • asthenia
  • fatigue
  • pain
  • edema
  • chest pain
  • erectile dysfunction
  • priapism
  • hypotension
  • flushing
  • facial flushing
  • thrombocytopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is best kept at a cool temperature below 30 degrees Celsius. Doing so will help maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

Round tablets that are white to light yellow in color

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.