Ultramac Tablets

Adult dose

Children over 12 years and adults: The dosage should be adjusted according to the patient's level of pain and response to treatment. An initial dose of 2 tablets is recommended, and thereafter the interval between doses should be at least 6 hours, not exceeding 8 tablets in a day. Administer the effective minimum dose for the shortest time possible. Avoid using this medication for a longer duration than necessary, and if long-term use is required due to the nature and severity of the condition, conduct regular monitoring to confirm the continuous use of this medication. Elderly Administer the typical adult dosage. However, in the case of elderly patients over 75 years old, oral administration of tramadol has shown a 17% increase in the elimination half-life, so doses should be given with a minimum interval of 6 hours. Renal impairment patients For moderate renal impairment (creatinine clearance of 10-30 ml/min), extend the dosing interval to 12 hours. Severe renal impairment patients (creatinine clearance of less than 10 ml/min) should not be administered this medication. Tramadol is removed very slowly during hemodialysis and filtration, so there is no need to re-administer this medication after dialysis to maintain analgesic effect. Hepatic impairment patients For patients with moderate hepatic impairment, it is advisable to consider extending the dosing interval carefully. Do not administer this medication to patients with severe hepatic impairment.

This medication may burden the liver; therefore, individuals who regularly consume more than three drinks of alcohol daily should consult a doctor or pharmacist before use. If skin rashes or allergic reactions occur while taking this medication, discontinue use immediately and consult a professional. The ingredients in this medication may cause seizures, so patients with a history of seizures or those at high risk of seizures should exercise special caution. Severe asthma patients may find it difficult to breathe with this medication, so it should only be used in medically equipped settings. Taking this medication with alcohol or sedatives can cause severe drowsiness, respiratory difficulties, or coma; therefore, co-administration should be avoided. Patients with head injuries or brain disorders should use this medication cautiously, as it can increase intracranial pressure. This medication may cause physical and psychological dependence, so strict adherence to a doctor's instructions is necessary for long-term use. Especially, patients with impaired liver or kidney function should adjust the dosage and intervals of this medication and consult a doctor. It is safe not to use this medication in children under 12 years old or in certain pediatric post-operative patients. Pregnant or breastfeeding women must consult a doctor before taking this medication and should preferably avoid use while nursing. This medication can cause drowsiness and dizziness, so be cautious when driving or operating hazardous machinery. In case of overdose, severe respiratory depression, seizures, liver damage, etc., may occur, so adherence to prescribed doses is critical, and immediate emergency treatment is required if overdose is suspected. There are many interactions with other drugs, so patients should inform healthcare providers about any medications they are taking, especially when combining with antidepressants, antibiotics, anticonvulsants, or sedatives. It is advisable to undergo regular health check-ups, including liver function and blood tests, while taking this medication. Keep out of reach of children and store safely to prevent misuse or abuse.

Serious side effects

• Hives, severe swelling (edema), difficulty breathing, cold sweat → severe allergic reactions
• Severe rashes with high fever, blisters, peeling skin, mucous membrane pain in the mouth/eyes → severe skin adverse reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever → respiratory problems
• Yellowing of the skin or eyes (jaundice), extreme lethargy → liver issues (jaundice)
• Sudden and very severe headaches, lightning.

Mild side effects

• Decreased appetite
• insomnia
• depression
• dizziness
• headache
• drowsiness
• nausea
• vomiting
• constipation
• dry mouth

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best kept in a cool place at room temperature (below 25 degrees). Storing it this way preserves its efficacy and prevents deterioration.

Appearance

Pale yellow rectangular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle