Viewing nowCombinationMaxnophen Semi Tablet
Tramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
Boryung (Co., Ltd.)

MFDS item code 200805296 · Notified 2008.05.09 · Insurance code 641904550
Relief of moderate to severe acute and chronic pain
This medication is used to relieve acute and chronic pain ranging from moderate to severe.
Children aged 12 and older and adults: The dosage should be adjusted according to the patient's level of pain and therapeutic response. It is recommended to administer an initial dose of 4 tablets, with subsequent doses taken at intervals of at least 6 hours, but not exceeding 16 tablets per day. Administer the effective lowest dose for the shortest duration possible. Do not prescribe this medication for longer than necessary, and if prolonged treatment is needed due to the nature and severity of the disease, regular monitoring should be conducted to determine whether continued administration of the medication is warranted. Elderly: Standard adult dosages should be administered, but for elderly patients over 75 years old, oral administration of tramadol may increase the elimination half-life by 17%, so this medication should be given at intervals of at least 6 hours. Renal impairment: For patients with moderate renal impairment (creatinine clearance 10-30 ml/min), the dosing interval should be extended to 12 hours. For patients with severe renal impairment (creatinine clearance less than 10 ml/min), administration of this medication is not recommended. Tramadol is eliminated very slowly during hemodialysis and filtration, so there is no need to readminister this medication to maintain analgesic effects post-dialysis. Hepatic impairment: For patients with moderate hepatic impairment, it should be considered carefully to extend the dosing interval. Administration of this medication is not recommended for patients with severe hepatic impairment.
Children aged 12 and older and adults: The dosage should be adjusted according to the patient's level of pain and therapeutic response. It is recommended to administer an initial dose of 4 tablets, with subsequent doses taken at intervals of at least 6 hours, but not exceeding 16 tablets per day.
This medication may put strain on the liver, so individuals who consume alcohol in amounts greater than a certain daily limit should consult a doctor or pharmacist. If a rash or allergic reaction occurs during treatment with this medication, stop taking it immediately and consult a healthcare professional. One of the ingredients in this medication, tramadol, may increase the risk of seizures, so caution is required if you have a history of seizures or are taking related medications. This medication should only be used in a medically supervised environment for patients with acute asthma, as it may worsen breathlessness. Concurrent use of this medication with alcohol or central nervous system depressants like sedatives may cause severe drowsiness or respiratory depression, so co-administration should be avoided. Patients with head injuries or brain diseases may experience increased confusion or respiratory issues when taking this medication, so caution is needed. This medication can lead to dependence, so strict management of dosage and duration is required under a physician's guidance when taken long-term. Patients with impaired liver function should consult a doctor before taking this medication, and it should not be taken with other acetaminophen products because of the risk of liver toxicity. This medication is not to be administered to children under the age of 12 or to adolescents under the age of 18 who have undergone tonsillectomy or adenoidectomy. Pregnant or breastfeeding women must consult a healthcare professional before taking this medication, as side effects such as sedation or respiratory depression may occur in the baby while breastfeeding. Caution is advised when driving or operating machinery due to potential drowsiness or dizziness, and the risk is heightened when taken with alcohol. Overdose of this medication can lead to severe respiratory depression, seizures, liver damage, and more, thus it is crucial to adhere strictly to the prescribed dosage. In case of overdose, seek emergency medical assistance immediately. When combined with other medications, there may be interactions, so all medications being taken should be disclosed to a doctor or pharmacist. This medication should be stored securely out of reach of children, and care should be taken to prevent misuse or accidental ingestion.
Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough and fever, yellowing of skin or eyes, extreme lethargy, sudden and severe headache, thunderclap headache, seizure, confusion, visual disturbances, paralysis, significantly reduced urine output
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly sealed container to prevent air exposure, and it is safe to keep it at room temperature between 1 to 30 degrees Celsius. Therefore, avoid extremely hot or cold places and maintain it in a suitable temperature environment.
Pale yellow rectangular film-coated tablet
30 tablets/bottle, 300 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowCombinationTramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
Boryung (Co., Ltd.)
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Yuyoung Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Youyoung Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 18.75mg · Acetaminophen 162.5mg
Tablet · Prescription medication · Combination
Korea Pharmaceutical Co., Ltd.
CombinationTramadol Hydrochloride 37.5mg · Acetaminophen 325mg
Tablet · Prescription medication · Combination
Korea United Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Shinpoong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 325mg · Tramadol Hydrochloride 37.5mg
Tablet · Prescription medication · Combination
Sinphong Pharmaceutical Co., Ltd.
CombinationAcetaminophen 162.5mg · Tramadol Hydrochloride 18.75mg
Tablet · Prescription medication · Combination
Albozen Korea Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.