Irbesartan Plus Tablet 150/12.5 mg

Adult dose

This medicine is administered once daily without regard to meals. 1. For patients whose blood pressure is not sufficiently controlled with monotherapy - Administer 1 tablet of Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg once daily - If blood pressure remains uncontrolled, administer 1 tablet of Irbesartan 300 mg/Hydrochlorothiazide 12.5 mg once daily - If blood pressure remains uncontrolled, administer 1 tablet of Irbesartan 300 mg/Hydrochlorothiazide 25 mg once daily. The dosage should not exceed Irbesartan 300 mg/Hydrochlorothiazide 25 mg. 2. For initial therapy in patients with moderate or severe hypertension (stage 2), individualization is required considering baseline blood pressure, treatment goals, and expected improvement in treatment goal achievement compared to monotherapy. Typically, therapy is initiated with 1 tablet of Irbesartan 150 mg/Hydrochlorothiazide 12.5 mg once daily, and if blood pressure control is necessary, the dosage may be increased to a maximum of Irbesartan 300 mg/Hydrochlorothiazide 25 mg after 1 to 2 weeks. The initiation of therapy in patients with intravascular volume depletion is not recommended.

This medicine can cause serious harm to the fetus if taken during pregnancy, especially during the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. Women who may become pregnant or are breastfeeding should not take this medicine. Patients with allergies to the ingredients in this medicine or those with certain kidney dysfunctions, anuria, etc., should also avoid this medicine. Patients with impaired kidney function or liver disorders should use this medicine cautiously, with regular blood tests to monitor kidney function and electrolyte status. This medicine may cause hypotension, leading to dizziness or fatigue, and caution is needed when driving or operating machinery. The hydrochlorothiazide component may cause photosensitivity, so exposure to UV light should be minimized, and any skin abnormalities should be discussed with a doctor immediately. This medicine can affect blood potassium levels, so potassium levels should be monitored regularly, and caution should be taken when used with potassium supplements or other medications. This medicine can interact with other antihypertensive medications or specific drugs, so patients should consult their doctor or pharmacist if they are taking any other medications. Its safety has not been established in children or adolescents, so it is not recommended. Elderly patients may be more sensitive to this medicine, so extra caution is needed when administering it. In cases of overdose, symptoms such as hypotension, electrolyte imbalance, and dehydration may occur, so immediate medical assistance is required. This medicine should be stored out of reach of children and kept in its original container.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis

Mild side effects

• Dizziness
• fatigue
• nausea/vomiting
• abnormal urination
• increased BUN
• elevated creatine kinase
• increased creatinine
• headache
• orthostatic dizziness
• fainting

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is safest to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle