Hexavit Injection (Pyridoxine Hydrochloride)

Adult dosage

If oral administration is difficult, administer Pyridoxine Hydrochloride as a muscle, subcutaneous or intravenous injection in divided doses of 10-100 mg per day. For vitamin B6 dependency, higher doses may be given. Adjust as appropriate depending on age and symptoms.

When using this medication in injection form, care should be taken when opening the ampoule as there is a risk of glass fragments mixing in. Extra caution is needed especially when administering to children or the elderly. This medication should not be given to patients who are allergic to its components or those currently taking levodopa. When taken orally, patients who are currently undergoing treatment or taking specific medications should consult a physician before use. Side effects such as photosensitivity reactions, nausea, headache, and drowsiness may occur, and prolonged high-dose use may lead to neurological symptoms, so caution is required. When administered as an injection, discomfort or pain may occur at the injection site. When administered in large doses to neonates or infants, serious side effects such as muscle damage and kidney dysfunction may arise, thus observation by medical personnel is necessary. The prescribed dosage and administration must be strictly followed, and if symptoms do not improve after one month of use, consultation with a specialist is advised. High-dose use during pregnancy may affect the newborn, and caution should be exercised, especially when administering to neonates or infants by gradually increasing the dose. Gradually tapering off this medication can help reduce side effects. There may be drug interactions, so caution must be taken to avoid concurrent use with levodopa, isoniazid, penicillamine, and estrogen preparations. Women who are pregnant or breastfeeding should consult with medical personnel regarding high doses of this medication. Extra caution must be taken regarding the possibility of side effects when administering to children or the elderly. This medication should be kept out of the reach of children and stored in a cool, dry place away from direct sunlight. Additionally, it should be stored in its original container to prevent degradation in quality or misuse.

Serious side effects

• Neuromuscular spasms
• peripheral paralysis
• sensory neuropathy accompanied by ataxia
• rhabdomyolysis
• acute renal failure
• liver dysfunction

Mild side effects

• Photosensitivity reaction
• nausea
• headache
• drowsiness
• discomfort during injection
• pain
• diarrhea
• vomiting

This medication should be stored in a dark container to prevent exposure to light, and it is better to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

A brown ampoule injection containing a colorless to yellowish liquid

Package unit

2mL X 50 ampoules