BioCap (Sodium Bicarbonate)

Adult administration

1. When using the specified acetate-containing dialysis solution (Solution A), this formulation creates approximately 180L of bicarbonate dialysis solution containing 38mEq/L of HCO3-. 2. In cases using the supply device for bicarbonate dialysis with a dilution ratio of Solution A 1 : (this medicine + purified water) 34, it is used for dialysis. 3. For preparing dialysis solution for one patient (based on 6 hours)

This medicine should not be used in patients with low blood pressure and rapid heartbeats. Patients with pulmonary edema or abnormalities in heart electrical signals may also be at risk when receiving this medicine. Patients with high blood potassium levels and those with coagulation issues should avoid this medication. Patients with severe liver disease or metabolic issues due to diabetes should use this medicine with caution. Patients taking digitalis for heart conditions may need to be careful as this medicine can lead to drug toxicity. Patients with elevated calcium and phosphorus levels before dialysis should be cautious when using this medicine due to potential calcium deposits. Patients with insufficient caloric intake or dietary restrictions due to diabetes should be cautious as there is a risk of hypoglycemia. This medication can cause hypoglycemia during dialysis, so if symptoms occur, sugars should be replenished immediately. Calcium levels may increase, and if necessary, dialysis solutions with lower calcium concentrations should be switched to. There is a possibility of bone diseases such as osteoporosis or osteomalacia, and therefore adequate treatment like vitamin D3 administration is necessary. If calcium deposits occur, phosphorus binders should be used to manage serum phosphorus levels. Symptoms of dialysis disequilibrium syndrome such as headache, nausea, vomiting, cramps, and altered consciousness may occur; thus, if symptoms arise, the dialysis speed should be reduced. If there are problems in the circulatory system that lead to a rapid drop in blood pressure or shock, dialysis should be stopped, or fluids and blood pressure-raising agents should be administered. Rarely, blood pressure may rise, so actions may be necessary to switch to antihypertensive agents or acetate dialysis solutions. This medication is used for dialysis in patients with chronic renal failure, particularly when metabolic acidosis is difficult to correct with solutions of high acetate concentration. It is also suitable for patients who have difficulty maintaining dialysis management due to risks such as disequilibrium syndrome or low blood pressure with high acetate concentration dialysis solutions. Additionally, it is used when adequate fluid removal is challenging. This medication is used in dialysis solutions that do not contain glucose, for patients who have difficulty controlling high blood sugar due to abnormal glucose metabolism. Regular blood tests are recommended during treatment to monitor electrolytes, acid-base balance, and blood sugar levels. Pregnant women or women who could become pregnant should use this medicine only when the potential benefits outweigh the risks, as its safety is not established. Safety in pediatric patients has not been sufficiently studied, and caution is necessary for use in this population. Elderly patients need to be careful when using this medicine, just like other patients, and regular checks and vitamin D3 administration are necessary due to the possibility of bone diseases from prolonged use. Dialysis dilution water must be strictly purified and stored in tightly sealed containers to prevent exposure to air or moisture. The medication should also be kept away from extreme heat or cold, preferably at a normal temperature between 1°C and 30°C.

Serious side effects

Altered consciousness

Mild side effects

Hypoglycemia, hypercalcemia, osteoporosis, osteomalacia, fibrous osteitis, ectopic calcification, symptoms of dialysis disequilibrium syndrome (headache, nausea, vomiting, cramps, malaise, fatigue), hypotension, hypertension, headache, palpitations, sense of paralysis in limbs, general fatigue, chest discomfort, sudden drops in blood pressure, altered consciousness

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, the medication should be kept away from extreme temperatures, ideally stored at normal room temperature between 1 to 30 degrees Celsius.

Appearance

White crystals or crystalline powder in a polypropylene container

Package unit

1 container (650g, 750g)