Gavsmate Tablet 50/850 mg

Adult dose

In the treatment of patients with type 2 diabetes, the dosage of this medication should be individualized based on efficacy and tolerability, not exceeding 100 mg of vildagliptin and 2000 mg of metformin. 1. In cases where there has been no previous experience with antidiabetic drug treatment and monotherapy does not adequately control blood sugar: The initial dosage is 50/500 mg of this medication taken once daily, gradually increasing to 50/1000 mg.

This medication can cause serious lactic acidosis or hypoglycemia, so it should not be used in patients at high risk for these conditions. It should not be administered to patients with significantly reduced kidney function, heart failure, or renal impairment due to acute myocardial infarction or sepsis. If undergoing tests using radiologic iodinated contrast agents, this medication should be discontinued 48 hours before the test and resumed only after confirming normal kidney function. Patients with an allergy to this medication, type 1 diabetes, diabetic ketoacidosis, or metabolic acidosis such as lactic acidosis should not receive this medication. Avoid use in patients with severe infections, severe trauma, malnutrition, liver dysfunction, pulmonary embolism, severe pulmonary dysfunction, excessive alcohol consumption, pregnant or breastfeeding women. Caution should be exercised in cases of irregular meals, intense exercise, or interactions with other medications. During treatment, symptoms such as headache, dizziness, nausea, and hypoglycemia may occur, and if adverse reactions are severe, consultation with a physician is advised. Regular liver function tests should be performed to monitor liver function, and kidney function should also be regularly monitored. Special care is required for the elderly, as they may experience reduced kidney function, necessitating dose adjustment and caution. Alcohol intake may increase the risk of lactic acidosis, so it is advisable to avoid alcohol during treatment. It is necessary to discontinue this medication for a period before and after surgery, and appropriate measures should be taken immediately if hypoglycemic symptoms occur. Women who are pregnant or breastfeeding should not use this medication, and it is also not recommended for children and adolescents under 18 years of age. In case of overdose, supportive therapy is necessary, and hemodialysis may be beneficial. This medication should be kept out of reach of children and should not be transferred to another container.

Serious side effects

Hives, angioedema, pancreatitis, hepatitis, blisters and exfoliative skin lesions, severe joint pain with disability, cutaneous vasculitis, cholecystitis, lactic acidosis, liver abnormalities (liver dysfunction and jaundice), severe hypoglycemia, severe edema, cardiovascular collapse (shock), acute myocardial infarction, sepsis, serious neurological symptoms (headache, confusion, visual disturbances, paralysis), respiratory problems (dyspnea, asthma attacks, accompanied by cough and fever).

Mild side effects

• Tremor
• headache
• dizziness
• fatigue
• nausea
• gastroesophageal reflux
• diarrhea
• abdominal distension
• chills
• decreased blood sugar

This medication is sensitive to air and moisture, so the container must be kept tightly sealed. Additionally, it is recommended to store the medication in a cool place below 30 degrees Celsius to maintain its efficacy.

Appearance

Yellow oval film-coated tablet

Package unit

60 tablets (10 tablets/PTP packaging × 6)