Medication info

Aizatan Plus Tablet

Prescription medicationTabletApproval withdrawn
Ingredient · strength
Irbesartan›150mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
동화약품(주)
Appearance
Pink, double-convex, elongated film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 200803386 · Notified 2008.03.27

This product's status changed to Approval withdrawn on 2024.01.25. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Management and treatment of essential hypertension
Who uses it
Adults · Children
Adult dosage
This medication is administered once daily without regard to meals. 1. For patients whose blood pressure is not adequately controlled by monotherapy: - Irbesartan 150 mg / Hydrochlorothiazide 12.5 mg once daily 1 tablet - Irbesartan 300 mg / Hydrochlorothiazide 12.5 mg once daily 1 tablet - Irbesartan 300 mg / Hydrochlorothiazide 25 mg once daily 1 tablet 2. For moderate or severe
Children's dosage
The safety and efficacy of this medication have not been established in pediatric patients and adolescents under 18 years of age.

Ingredients

Manufacturer
동화약품(주)

Efficacy & effects

Management and treatment of essential hypertension

  • Essential hypertension
  • moderate hypertension
  • severe hypertension
View approved original text

This medication is used for patients with essential hypertension. It is administered to those whose blood pressure is not adequately controlled by monotherapy, and in the initial treatment of patients with moderate to severe hypertension (stage 2) who require combination therapy to reach treatment goals. This effectively manages blood pressure and improves health.

Dosage and Administration

Adult dosage

This medication is administered once daily without regard to meals. 1. For patients whose blood pressure is not adequately controlled by monotherapy: - Irbesartan 150 mg / Hydrochlorothiazide 12.5 mg once daily 1 tablet - Irbesartan 300 mg / Hydrochlorothiazide 12.5 mg once daily 1 tablet - Irbesartan 300 mg / Hydrochlorothiazide 25 mg once daily 1 tablet 2. For moderate or severe

Children's dosage

The safety and efficacy of this medication have not been established in pediatric patients and adolescents under 18 years of age.

Precautions

This medication can cause serious harm to the fetus and newborn if administered to pregnant women, so it must be discontinued immediately if pregnancy is confirmed. Women who may become pregnant or are breastfeeding, individuals with allergies to specific medications, and patients with severe renal impairment should not use this drug. Special precautions are necessary for patients with hypotension, renal function problems, liver disease, or specific cardiac conditions when using this drug. While taking this medication, side effects such as dizziness, fatigue, nausea, vomiting, and abnormal urination may occur, and there may be an increased risk of skin cancer, so sun exposure should be avoided and skin condition should be monitored periodically. Caution should be taken while driving or operating machinery as dizziness or fatigue may occur, and if symptoms of excessively low blood pressure arise, immediate consultation with medical personnel is required. This medication can be used with other antihypertensive medications, but interactions may occur with lithium, certain diuretics, and potassium-related drugs, so it's important to inform healthcare providers about all medications being taken. It is safest to avoid use during pregnancy or breastfeeding, especially during breastfeeding, as it may affect the baby through breast milk. Safety and efficacy have not been established for children and adolescents, so it is not recommended for them. Elderly patients may be more sensitive to this medication, so caution is advised when using it. Patients should have their renal function and electrolyte status regularly checked through blood tests, and any abnormal symptoms should be reported to healthcare providers immediately. In case of overdose, symptoms such as hypotension, electrolyte imbalances, and dehydration may occur, so it is critical to adhere strictly to the prescribed dosage, and any issues should prompt immediate emergency treatment. This medication should be kept out of the reach of children and stored in its original container to prevent quality deterioration and misuse.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucous membranes, difficulty or problems breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, consciousness confusion, visual disturbances, paralysis,

Mild side effects

  • Dizziness
  • fatigue
  • nausea/vomiting
  • abnormal urination
  • elevated BUN
  • elevated creatine kinase
  • elevated creatinine
  • orthostatic dizziness
  • headache
  • fainting
Show 22 more
  • hypotension
  • tachycardia
  • edema
  • flushing
  • cough
  • diarrhea
  • dyspepsia
  • taste disturbances
  • hepatitis
  • abnormal liver function
  • sexual dysfunction
  • changes in libido
  • limb edema
  • arthralgia
  • myalgia
  • tinnitus
  • thrombocytopenia
  • depression
  • sleep disorders
  • orthostatic hypotension
  • arrhythmia
  • aplastic anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It is advisable to keep the storage temperature between 1 degree and 30 degrees Celsius room temperature. Proper storage will help maintain the drug's effectiveness.

Appearance and packaging

Appearance

Pink, double-convex, elongated film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.