Closen Tablets (Clonixin Lysinate)

Adult dosage

Administer clonixin lysinate 125∼250 mg orally 3 times daily.

This medication may cause gastrointestinal bleeding in those who regularly consume more than three alcoholic drinks a day, so it is essential to consult a doctor or pharmacist. This medication can affect the cardiovascular system and increase the risk of myocardial infarction or stroke, so those with cardiovascular diseases or risk factors should exercise greater caution. Serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, or perforation may occur, so elderly patients or those with a history of gastrointestinal diseases should take it with care. Individuals with a history of peptic ulcers or gastrointestinal bleeding, those allergic to this medication’s ingredients, pregnant women or women who may become pregnant, and patients with severe liver, kidney, or heart diseases should not take this medication. This medication contains yellow dye, so individuals with allergic reactions to it should be cautious. When taken with other non-steroidal anti-inflammatory drugs, ACE inhibitors, aspirin, diuretics, lithium, methotrexate, anticoagulants, immunosuppressants, antidepressants, corticosteroids, etc., the risk of interactions and side effects may increase, so consultation with healthcare professionals is essential. If abnormal symptoms such as gastrointestinal symptoms (nausea, vomiting, abdominal pain, etc.), skin rashes, anemia, liver function anomalies, or drowsiness occur, discontinue use immediately and consult a doctor. Take this medication only at the minimal dose and for the shortest duration possible, and regular blood tests and liver and kidney function tests are required for long-term use. Patients with hypertension, heart failure, or kidney disease should closely monitor blood pressure and fluid status, and this medication should be used carefully in conjunction with appropriate antibiotics for treating infectious inflammation. Pregnant or breastfeeding women should avoid taking this medication or consult with healthcare professionals, and breastfeeding should be stopped if necessary. Store this medication out of reach of children, and take care not to transfer it to another container.

gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding in the stomach or intestines, ulcers, perforation, nausea, vomiting, diarrhea, constipation, abdominal pain, peptic ulcers, shock, rash, itching, anemia, elevated AST, elevated ALT, drowsiness, headache, dizziness, cold sweat, chill, abnormal euphoria, jaundice, fulminant hepatitis, liver necrosis, liver failure, anemia, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, severe bronchospasm

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius to ensure the medication's effectiveness and safety.

Appearance

Orange round film-coated tablet

Package unit

10 tablets (10 tablets/PTP)