Medication info
Tobast Tablet 10 mg (Atorvastatin Calcium Trihydrate)

Tobast Tablet 10 mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
Light yellow oval film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200801352 · Notified 2008.01.31 · Insurance code 643504090

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia.
Who takes it
Adults · Children
Adult dose
For the treatment of hyperlipidemia, the recommended initial dosage is 10 mg of atorvastatin once daily. If a greater reduction in LDL cholesterol is needed, it may start at 20 mg or 40 mg once daily. The medication is administered in a range of 10-80 mg once daily. Initial and maintenance dosages should be individualized based on treatment goals and responses.
Child dose
For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended initial dosage is 10 mg daily, with a maximum dosage of 20 mg daily. The dosage may be adjusted based on therapy goals.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia.

  • Coronary heart disease
  • myocardial infarction
  • stroke
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • hyperlipidemia
  • primary hypercholesterolemia
  • mixed dyslipidemia
  • abnormal beta-lipoproteinemia
  • increased serum triglycerides
View approved original text

This medication helps reduce the risk of cardiovascular diseases. Specifically, it decreases the risk of myocardial infarction, stroke, vascular procedures, and angina in adults with various risk factors for coronary heart disease (e.g., age, smoking, hypertension). It is also effective in reducing hospitalization risks due to myocardial infarction, stroke, and congestive heart failure in patients with type 2 diabetes or those with pre-existing heart conditions. This medication is used to treat hyperlipidemia and specifically reduces high LDL cholesterol and total cholesterol while increasing good HDL cholesterol, improving lipid levels in the blood. It is also used as an adjunct to dietary therapy in patients with hypercholesterolemia and dyslipidemia and helps reduce cholesterol levels in young pediatric patients when certain criteria are met. Overall, it is used to improve cardiovascular health and lower the risk of related diseases.

How to take

Adult dose

For the treatment of hyperlipidemia, the recommended initial dosage is 10 mg of atorvastatin once daily. If a greater reduction in LDL cholesterol is needed, it may start at 20 mg or 40 mg once daily. The medication is administered in a range of 10-80 mg once daily. Initial and maintenance dosages should be individualized based on treatment goals and responses.

Child dose

For pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia, the recommended initial dosage is 10 mg daily, with a maximum dosage of 20 mg daily. The dosage may be adjusted based on therapy goals.

Precautions

This medication may cause muscle problems, so if symptoms of muscle pain or weakness occur, use should be discontinued immediately and a doctor should be consulted. This medication should not be used by patients with allergic reactions or severe liver disease, those with muscle disorders, pregnant women, or breastfeeding women, and in children under 10 years. Patients with impaired liver or kidney function should use this medication cautiously, as a decline in liver function may increase drug concentration, requiring careful monitoring. While taking this medication, regular liver function tests and muscle-related tests should be performed, and any unusual symptoms should be reported to healthcare professionals immediately. This medication interacts with several other medications, so patients should inform their doctor or pharmacist about any other medications they are taking, especially when taken with certain antibiotics, antifungals, antivirals, or grapefruit juice. Women of childbearing age should use appropriate contraception while taking this medication and discontinue it immediately if pregnancy is confirmed. This medication is not recommended for breastfeeding women. If breastfeeding, it should be avoided. Elderly patients or those with decreased kidney function are at higher risk for muscle-related side effects when using this medication and require closer monitoring. There is no specific antidote for overdose; treatment should be symptom-based, and liver function and muscle condition should be monitored. Keep this medication out of reach of children and store it in its original container to prevent misuse or degradation of quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

  • Fatigue
  • malaise
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • throat and laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headaches
  • dizziness
  • paresthesia
  • sensory loss
  • taste disorder
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture, and it should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

Light yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.