Alendronate Sodium Hydrate 35 mg Tablet

Adult dose

Adults: Administer 35 mg of risedronate sodium orally once weekly. No dosage adjustment is necessary in elderly patients (over 60 years of age), because the bioavailability and pharmacodynamics of this medicine are similar to those in younger people. No dosage adjustment is necessary in patients with a creatinine clearance of 30 mL/min or higher. This medicine is contraindicated in patients with severe renal impairment and a creatinine clearance below 30 mL/min. Because food interferes with the absorption of this medicine, take it at least 30 minutes before breakfast to ensure adequate absorption, or take it at any time of day at least 2 hours before or after consuming food or beverages. To allow this medicine to reach the stomach easily and reduce the possibility of esophageal irritation, take it in an upright position with a sufficient amount of plain water (170 ∼ 230 mL). Taking this medicine with other beverages, including mineral water, may reduce its absorption. Do not chew or suck this medicine because of the possibility of oropharyngeal ulceration. Patients should not lie down for at least 30 minutes after taking it. If a patient forgets to take the medicine on the scheduled day, they should take it the next morning when they remember. The next dose should then be taken on the originally scheduled day. Do not take 2 tablets on the same day.

Child dose

The safety and efficacy in children under 18 years of age have not been established.

This medication may irritate the mucous membranes of the stomach and esophagus, so patients with gastritis or esophageal diseases should be especially cautious. Serious side effects such as esophagitis or esophageal ulcers can occur, so it is essential to take it with plenty of water after ingestion and not lie down for 30 minutes afterwards. If symptoms such as difficulty swallowing, chest pain, or heartburn occur during the use of this medication, immediately stop taking it and consult a doctor. This medication should not be used in patients with esophageal dysfunction, hypocalcemia, pregnant or breastfeeding women, or patients with severely impaired kidney function. Rarely, during prolonged use, serious side effects such as osteonecrosis of the jaw or atypical fractures may occur, so patients should immediately inform their healthcare provider if any unusual symptoms arise during treatment. Taking this medication along with drugs or foods containing calcium, magnesium, iron, etc., can interfere with its absorption, so it is essential to space out the ingestion time sufficiently. Pregnant or breastfeeding women should avoid taking this medication, and safety for children has not been established. In case of overdose, blood calcium levels may drop, leading to hypocalcemia symptoms, so it is imperative to visit a medical institution immediately. This medication should be stored out of reach of children, and it is safer not to transfer it to another container.

• esophagitis
• esophageal ulcer
• esophageal erosion
• esophageal obstruction
• esophageal perforation
• bleeding
• infection
• low back pain
• accidental injury
• pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and kept at room temperature between 1 and 30 degrees Celsius. By storing it this way, the effects of the medication can be maintained for a long time.

Appearance

Pale orange rectangular film-coated tablet

Package unit

4 tablets (4 tablets/PTP packaging x 1)